Reactome | CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-CFA-3229098] CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] - Canis familiaris
consumedByEvent	[Reaction:R-CFA-3229089] PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter - Canis familiaris [Reaction:R-CFA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter - Canis familiaris
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10281906
displayName	CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm]
hasComponent	[GenomeEncodedEntity:R-CFA-3200017] Ghost homologue of CDKN2A gene [nucleoplasm] [Complex:R-CFA-433757] Nucleosome with H3K27me3 [nucleoplasm]
inDisease	false
inferredFrom	[Complex:R-HSA-3222570] CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] - Homo sapiens
maxDepth	5
name	CDKN2A Gene:H3K27Me3-Nucleosome
producedByEvent	[Reaction:R-CFA-3240295] PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-3222570
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-CFA-3229089] PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter [Reaction:R-CFA-3222593] KDM6B demethylates H3K27me3 on p16INK4A promoter
(output)	[Reaction:R-CFA-3240295] PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter
(hasComponent)	[Complex:R-CFA-3229098] CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm]
(inferredTo)	[Complex:R-HSA-3222570] CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm]