Reactome | p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-CFA-2424486] Phosphorylation and activation of VAV2/VAV3 by SYK - Canis familiaris [Reaction:R-CFA-2424484] Phosphorylation of BTK by p-SYK - Canis familiaris
created	[InstanceEdit:10098795] Wright, Adam, 2024-03-07
dbId	10153520
displayName	p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane]
hasComponent	[EntityWithAccessionedSequence:R-CFA-197948] BTK [cytosol] [Complex:R-CFA-2424460] p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG [plasma membrane] [SimpleEntity:R-ALL-179838] PI(3,4,5)P3 [plasma membrane] [DefinedSet:R-CFA-2424458] VAV2,VAV3 [cytosol]
inDisease	false
inferredFrom	[Complex:R-HSA-2424461] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane] - Homo sapiens
name	p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3
producedByEvent	[Reaction:R-CFA-2424481] Recruitment of VAV and BTK to p-SLP-76 - Canis familiaris
schemaClass	Complex
species	[Species:49646] Canis familiaris
stId	R-CFA-2424461
summation	[Summation:9864367] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-CFA-2424486] Phosphorylation and activation of VAV2/VAV3 by SYK [Reaction:R-CFA-2424484] Phosphorylation of BTK by p-SYK
(output)	[Reaction:R-CFA-2424481] Recruitment of VAV and BTK to p-SLP-76
(inferredTo)	[Complex:R-HSA-2424461] p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane]

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