Reactome | Extension of pseudopodia by myosin-X in a PI3K dependent manner

Schema > Reaction > Entries

Extension of pseudopodia by myosin-X in a PI3K dependent manner Show undefined attributes

catalystActivity	[CatalystActivity:10271932] cytoskeletal motor activity of Myosin-X dimer [cytosol]
category	transition
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10271934
displayName	Extension of pseudopodia by myosin-X in a PI3K dependent manner
eventOf	[Pathway:R-CFA-2029482] Regulation of actin dynamics for phagocytic cup formation - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [Complex:R-CFA-1861699] Mother filament:branching complex:daughter filament [cytosol] [Complex:R-CFA-1861665] Myosin-X dimer [cytosol] [SimpleEntity:R-ALL-202247] PI(3,4)P2 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	Extension of pseudopodia by myosin-X in a PI3K dependent manner
output	[Complex:R-CFA-1861625] Actin filament bound Myosin-X [plasma membrane] [SimpleEntity:R-ALL-29372] Pi [cytosol]
precedingEvent	[Reaction:R-CFA-2029271] PI3K phosphorylates PIP2 to PIP3 - Canis familiaris [BlackBoxEvent:R-CFA-2029473] Branching and elongation of mother and daughter filaments - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-1861595
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-2029482] Regulation of actin dynamics for phagocytic cup formation
(inferredTo)	[Reaction:R-HSA-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner

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