Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Schema
>
SimpleEntity
>
Entries
PI(3,4)P2 [plasma membrane]
Show undefined attributes
Go to Details
authored
[InstanceEdit:201662] Garapati, P V, 2007-09-05 10:24:22
compartment
[Compartment:876] plasma membrane
componentOf
[Complex:R-CFA-8870324] PTPN13:PLEKHA1,2:PIP2 [plasma membrane] - Canis familiaris
[Complex:R-CFA-1861625] Actin filament bound Myosin-X [plasma membrane] - Canis familiaris
consumedByEvent
[Reaction:R-PFA-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Plasmodium falciparum
[Reaction:R-RNO-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Rattus norvegicus
[Reaction:R-CFA-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Canis familiaris
[Reaction:R-SCE-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Saccharomyces cerevisiae
[Reaction:R-SCE-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Saccharomyces cerevisiae
[Reaction:R-SPO-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Schizosaccharomyces pombe
[Reaction:R-SPO-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Schizosaccharomyces pombe
[Reaction:R-DDI-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Dictyostelium discoideum
[Reaction:R-DDI-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Dictyostelium discoideum
[Reaction:R-CEL-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Caenorhabditis elegans
[Reaction:R-CEL-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Caenorhabditis elegans
[Reaction:R-CEL-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Caenorhabditis elegans
[Reaction:R-DME-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Drosophila melanogaster
[Reaction:R-DME-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Drosophila melanogaster
[Reaction:R-DME-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Drosophila melanogaster
[Reaction:R-GGA-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Gallus gallus
[Reaction:R-GGA-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Gallus gallus
[Reaction:R-GGA-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Gallus gallus
[Reaction:R-XTR-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Xenopus tropicalis
[Reaction:R-MMU-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Mus musculus
[Reaction:R-MMU-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Mus musculus
[Reaction:R-MMU-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Mus musculus
[Reaction:R-HSA-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Homo sapiens
[Reaction:R-HSA-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Homo sapiens
[Reaction:R-HSA-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Homo sapiens
[Reaction:R-RNO-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Rattus norvegicus
[Reaction:R-RNO-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Rattus norvegicus
[Reaction:R-CFA-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Canis familiaris
[Reaction:R-CFA-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Canis familiaris
[Reaction:R-HSA-1675834] PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane - Homo sapiens
[Reaction:R-MMU-1676139] PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane - Mus musculus
[Reaction:R-BTA-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Bos taurus
[Reaction:R-BTA-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Bos taurus
[Reaction:R-BTA-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Bos taurus
[Reaction:R-SSC-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Sus scrofa
[Reaction:R-SSC-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Sus scrofa
[Reaction:R-SSC-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Sus scrofa
[Reaction:R-DRE-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Danio rerio
[Reaction:R-DRE-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane - Danio rerio
[Reaction:R-DRE-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Danio rerio
[Reaction:R-XTR-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane - Xenopus tropicalis
[Reaction:R-XTR-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane - Xenopus tropicalis
[Reaction:R-GGA-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2 - Gallus gallus
[Reaction:R-SSC-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2 - Sus scrofa
[Reaction:R-BTA-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2 - Bos taurus
[Reaction:R-CFA-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2 - Canis familiaris
[Reaction:R-RNO-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2 - Rattus norvegicus
[Reaction:R-MMU-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2 - Mus musculus
[Reaction:R-HSA-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2 - Homo sapiens
[Reaction:R-SSC-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner - Sus scrofa
[Reaction:R-BTA-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner - Bos taurus
[Reaction:R-CFA-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner - Canis familiaris
[Reaction:R-RNO-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner - Rattus norvegicus
[Reaction:R-MMU-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner - Mus musculus
[Reaction:R-HSA-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner - Homo sapiens
created
[InstanceEdit:202250] Garapati, P V, 2007-10-29 14:08:25
dbId
202247
displayName
PI(3,4)P2 [plasma membrane]
inDisease
false
memberOf
[DefinedSet:R-ALL-202277] PIP3, PI(3,4)P2 [plasma membrane]
modified
[InstanceEdit:9619952] Wu, G, 2018-09-19
name
PI(3,4)P2
1-phosphatidyl-1D-myo-inositol 3,4-bisphosphates
1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate
positivelyRegulates
[PositiveRegulation:R-HSA-8868077] Positive regulation by 'PI(3,4)P2 [plasma membrane]'
producedByEvent
[Reaction:R-DDI-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 - Dictyostelium discoideum
[Reaction:R-CEL-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 - Caenorhabditis elegans
[Reaction:R-DME-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 - Drosophila melanogaster
[Reaction:R-GGA-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 - Gallus gallus
[Reaction:R-SSC-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 - Sus scrofa
[Reaction:R-BTA-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 - Bos taurus
[Reaction:R-CFA-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 - Canis familiaris
[Reaction:R-RNO-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 - Rattus norvegicus
[Reaction:R-MMU-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 - Mus musculus
[Reaction:R-HSA-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 - Homo sapiens
[Reaction:R-GGA-202237] Hydrolysis of PIP3 to PI(3,4)P2 - Gallus gallus
[Reaction:R-XTR-202237] Hydrolysis of PIP3 to PI(3,4)P2 - Xenopus tropicalis
[Reaction:R-SSC-202237] Hydrolysis of PIP3 to PI(3,4)P2 - Sus scrofa
[Reaction:R-BTA-202237] Hydrolysis of PIP3 to PI(3,4)P2 - Bos taurus
[Reaction:R-CFA-202237] Hydrolysis of PIP3 to PI(3,4)P2 - Canis familiaris
[Reaction:R-RNO-202237] Hydrolysis of PIP3 to PI(3,4)P2 - Rattus norvegicus
[Reaction:R-MMU-202237] Hydrolysis of PIP3 to PI(3,4)P2 - Mus musculus
[Reaction:R-HSA-202237] Hydrolysis of PIP3 to PI(3,4)P2 - Homo sapiens
[Reaction:R-PFA-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Plasmodium falciparum
[Reaction:R-PFA-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Plasmodium falciparum
[Reaction:R-RNO-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Rattus norvegicus
[Reaction:R-SCE-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Saccharomyces cerevisiae
[Reaction:R-SCE-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Saccharomyces cerevisiae
[Reaction:R-SPO-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Schizosaccharomyces pombe
[Reaction:R-DDI-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Dictyostelium discoideum
[Reaction:R-DDI-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Dictyostelium discoideum
[Reaction:R-DDI-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Dictyostelium discoideum
[Reaction:R-CEL-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Caenorhabditis elegans
[Reaction:R-CEL-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Caenorhabditis elegans
[Reaction:R-CEL-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Caenorhabditis elegans
[Reaction:R-DME-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Drosophila melanogaster
[Reaction:R-DME-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Drosophila melanogaster
[Reaction:R-DME-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Drosophila melanogaster
[Reaction:R-GGA-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Gallus gallus
[Reaction:R-GGA-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Gallus gallus
[Reaction:R-GGA-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Gallus gallus
[Reaction:R-XTR-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Xenopus tropicalis
[Reaction:R-MMU-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Mus musculus
[Reaction:R-MMU-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Mus musculus
[Reaction:R-MMU-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Mus musculus
[Reaction:R-HSA-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Homo sapiens
[Reaction:R-HSA-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Homo sapiens
[Reaction:R-HSA-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Homo sapiens
[Reaction:R-RNO-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Rattus norvegicus
[Reaction:R-RNO-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Rattus norvegicus
[Reaction:R-CFA-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Canis familiaris
[Reaction:R-CFA-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Canis familiaris
[Reaction:R-CFA-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Canis familiaris
[Reaction:R-BTA-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Bos taurus
[Reaction:R-BTA-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Bos taurus
[Reaction:R-BTA-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Bos taurus
[Reaction:R-SSC-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Sus scrofa
[Reaction:R-SSC-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Sus scrofa
[Reaction:R-SSC-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Sus scrofa
[Reaction:R-DRE-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane - Danio rerio
[Reaction:R-DRE-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Danio rerio
[Reaction:R-DRE-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Danio rerio
[Reaction:R-XTR-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane - Xenopus tropicalis
[Reaction:R-XTR-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane - Xenopus tropicalis
referenceEntity
[ReferenceMolecule:202393] 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate [ChEBI:16152]
referenceType
ReferenceMolecule
schemaClass
SimpleEntity
stId
R-ALL-202247
Referrals
(hasComponent)
[Complex:R-CFA-8870324] PTPN13:PLEKHA1,2:PIP2 [plasma membrane]
[Complex:R-RNO-8870324] PTPN13:PLEKHA1,2:PIP2 [plasma membrane]
[Complex:R-BTA-8870324] PTPN13:PLEKHA1,2:PIP2 [plasma membrane]
[Complex:R-GGA-8870324] PTPN13:PLEKHA1,2:PIP2 [plasma membrane]
[Complex:R-SSC-8870324] PTPN13:PLEKHA1,2:PIP2 [plasma membrane]
[Complex:R-MMU-8870324] PTPN13:PLEKHA1,2:PIP2 [plasma membrane]
[Complex:R-HSA-8870324] PTPN13:PLEKHA1,2:PIP2 [plasma membrane]
[Complex:R-GGA-8941238] SH3PXD2A:PI(3,4)P2 [plasma membrane]
[Complex:R-SSC-8941238] SH3PXD2A:PI(3,4)P2 [plasma membrane]
[Complex:R-SPO-8941238] SH3PXD2A:PI(3,4)P2 [plasma membrane]
[Complex:R-RNO-8941238] SH3PXD2A:PI(3,4)P2 [plasma membrane]
[Complex:R-CFA-8941238] SH3PXD2A:PI(3,4)P2 [plasma membrane]
[Complex:R-DRE-8941238] SH3PXD2A:PI(3,4)P2 [plasma membrane]
[Complex:R-SCE-8941238] SH3PXD2A:PI(3,4)P2 [plasma membrane]
[Complex:R-MMU-8941238] SH3PXD2A:PI(3,4)P2 [plasma membrane]
[Complex:R-HSA-8941238] SH3PXD2A:PI(3,4)P2 [plasma membrane]
[Complex:R-CFA-1861625] Actin filament bound Myosin-X [plasma membrane]
[Complex:R-MMU-1861625] Actin filament bound Myosin-X [plasma membrane]
[Complex:R-BTA-1861625] Actin filament bound Myosin-X [plasma membrane]
[Complex:R-RNO-1861625] Actin filament bound Myosin-X [plasma membrane]
[Complex:R-SSC-1861625] Actin filament bound Myosin-X [plasma membrane]
[Complex:R-HSA-1861625] Actin filament bound Myosin-X [plasma membrane]
(input)
[Reaction:R-GGA-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2
[Reaction:R-SSC-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2
[Reaction:R-BTA-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2
[Reaction:R-CFA-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2
[Reaction:R-RNO-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2
[Reaction:R-MMU-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2
[Reaction:R-HSA-8870332] PTPN13:PLEKHA1,2 bind PI(3,4)P2
[Reaction:R-SSC-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner
[Reaction:R-BTA-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner
[Reaction:R-CFA-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner
[Reaction:R-RNO-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner
[Reaction:R-MMU-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner
[Reaction:R-HSA-1861595] Extension of pseudopodia by myosin-X in a PI3K dependent manner
[Reaction:R-PFA-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-RNO-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-CFA-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-SCE-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-SCE-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-SPO-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-SPO-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-DDI-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-DDI-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-CEL-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-CEL-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane
[Reaction:R-CEL-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-DME-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-DME-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-DME-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane
[Reaction:R-GGA-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane
[Reaction:R-GGA-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-GGA-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-XTR-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-MMU-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane
[Reaction:R-MMU-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-MMU-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-HSA-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane
[Reaction:R-HSA-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-HSA-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-RNO-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-RNO-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane
[Reaction:R-CFA-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane
[Reaction:R-CFA-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-HSA-1675834] PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane
[Reaction:R-MMU-1676139] PI(3,4)P2 is transported from the plasma membrane to the early endosome membrane
[Reaction:R-BTA-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane
[Reaction:R-BTA-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-BTA-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-SSC-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-SSC-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane
[Reaction:R-SSC-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-DRE-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane
[Reaction:R-DRE-1675773] PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane
[Reaction:R-DRE-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-XTR-1676149] PI(3,4)P2 is dephosphorylated to PI4P by PTEN at the plasma membrane
[Reaction:R-XTR-1676164] PI(3,4)P2 is dephosphorylated to PI3P by INPP4A/B at the plasma membrane
(output)
[Reaction:R-DDI-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
[Reaction:R-CEL-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
[Reaction:R-DME-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
[Reaction:R-GGA-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
[Reaction:R-SSC-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
[Reaction:R-BTA-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
[Reaction:R-CFA-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
[Reaction:R-RNO-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
[Reaction:R-MMU-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
[Reaction:R-HSA-8868072] Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2
[Reaction:R-GGA-202237] Hydrolysis of PIP3 to PI(3,4)P2
[Reaction:R-XTR-202237] Hydrolysis of PIP3 to PI(3,4)P2
[Reaction:R-SSC-202237] Hydrolysis of PIP3 to PI(3,4)P2
[Reaction:R-BTA-202237] Hydrolysis of PIP3 to PI(3,4)P2
[Reaction:R-CFA-202237] Hydrolysis of PIP3 to PI(3,4)P2
[Reaction:R-RNO-202237] Hydrolysis of PIP3 to PI(3,4)P2
[Reaction:R-MMU-202237] Hydrolysis of PIP3 to PI(3,4)P2
[Reaction:R-HSA-202237] Hydrolysis of PIP3 to PI(3,4)P2
[Reaction:R-PFA-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-PFA-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-RNO-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-SCE-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-SCE-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-SPO-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-DDI-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-DDI-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-DDI-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-CEL-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-CEL-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-CEL-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-DME-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-DME-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-DME-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-GGA-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-GGA-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-GGA-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-XTR-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-MMU-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-MMU-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-MMU-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-HSA-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-HSA-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-HSA-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-RNO-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-RNO-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-CFA-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-CFA-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-CFA-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-BTA-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-BTA-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-BTA-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-SSC-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-SSC-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-SSC-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-DRE-1676145] PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane
[Reaction:R-DRE-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
[Reaction:R-DRE-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-XTR-1676109] PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane
[Reaction:R-XTR-1675949] PI(3,4,5)P3 is dephosphorylated to PI(3,4)P2 by INPP5[2] at the plasma membrane
(hasMember)
[DefinedSet:R-ALL-202277] PIP3, PI(3,4)P2 [plasma membrane]
(regulator)
[PositiveRegulation:R-HSA-8868077] Positive regulation by 'PI(3,4)P2 [plasma membrane]'
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text