Reactome | Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2

Schema > Reaction > Entries

Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 Show undefined attributes

catalystActivity	[CatalystActivity:10239735] cyclin-dependent protein serine/threonine kinase activity of CCNB1:p-T161-CDK1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10226222] Weiser, Joel, 2026-03-16
dbId	10239737
displayName	Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2
eventOf	[Pathway:R-CFA-176417] Phosphorylation of Emi1 - Canis familiaris
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-174122] Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2 - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-CFA-188679] Emi1:Cdc20/Cdh1 complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-CFA-186975] Phospho-Emi1(Ser 182):Cdc20/Cdh1 complexes [nucleoplasm]
precedingEvent	[Reaction:R-CFA-174235] Association of Emi1 with Cdc20 - Canis familiaris [Reaction:R-CFA-174097] Association of Emi1 with Cdh1 - Canis familiaris [Reaction:R-CFA-170153] Dephosphorylation of nuclear Cyclin B1:phospho-Cdc2 (Thr 14, Tyr15) complexes by Cdc25 phosphatases - Canis familiaris
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:49646] Canis familiaris
stId	R-CFA-174122
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CFA-176417] Phosphorylation of Emi1
(inferredTo)	[Reaction:R-HSA-174122] Phosphorylation of the Emi1 DSGxxS degron by Cyclin B:Cdc2

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