Reactome | SGK phosphorylates SRF

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SGK phosphorylates SRF Show undefined attributes

catalystActivity	[CatalystActivity:10987246] protein serine/threonine kinase activity of p-T256,S422-SGK1 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10987258
displayName	SGK phosphorylates SRF
eventOf	[Pathway:R-CEL-9031628] NGF-stimulated transcription - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9612509] SGK phosphorylates SRF - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [EntityWithAccessionedSequence:R-CEL-5666000] unc-120 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	SGK phosphorylates SRF
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [EntityWithAccessionedSequence:R-CEL-9612518] phospho-unc-120 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-9612509
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-9031628] NGF-stimulated transcription
(inferredTo)	[Reaction:R-HSA-9612509] SGK phosphorylates SRF