Reactome | age-1 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

age-1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-CEL-3080565] K63polyUb-PI3K alpha [cytosol] - Caenorhabditis elegans [Complex:R-CEL-1250508] NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] - Caenorhabditis elegans
consumedByEvent	[Reaction:R-CEL-5654640] Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA - Caenorhabditis elegans [Reaction:R-CEL-5654614] Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA - Caenorhabditis elegans
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10918741
displayName	age-1 [cytosol]
endCoordinate	1068
inDisease	false
inferredFrom	[DefinedSet:R-HSA-74689] PI3K-catalytic subunit [cytosol] - Homo sapiens [EntityWithAccessionedSequence:R-HSA-74787] PIK3CA [cytosol] - Homo sapiens
maxDepth	1
name	age-1 PIK3CA Q94125
referenceEntity	[ReferenceGeneProduct:uniprot:Q94125] UniProt:Q94125
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-74787
startCoordinate	1

Referrals

(activeUnit)	[CatalystActivity:10928327] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of Active ALK:PI3K [plasma membrane] [CatalystActivity:10925776] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] [CatalystActivity:10924872] 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity of EGF-like ligands:p-6Y-EGFR:GRB2:p-5Y-GAB1:PI3K [plasma membrane]
(hasComponent)	[Complex:R-CEL-3080565] K63polyUb-PI3K alpha [cytosol] [Complex:R-CEL-1806182] PIK3CA:PIK3R3 [cytosol] [Complex:R-CEL-1806270] PIK3CA:PIK3R2 [cytosol] [Complex:R-CEL-5654187] Activated FGFR4:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] [Complex:R-CEL-5654190] Activated FGFR2:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] [Complex:R-CEL-5654205] Activated FGFR1:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] [Complex:R-CEL-5654192] Activated FGFR2:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] [Complex:R-CEL-5654195] Activated FGFR3:p-FRS2:GRB2:GAB1:PI3K [plasma membrane] [Complex:R-CEL-5654197] Activated FGFR3:p-FRS2:p-PTPN11:GRB2:GAB1:PI3K [plasma membrane] [Complex:R-CEL-1250508] NRG1/2:p-ERBB3:p-ERBB2:PI3K [plasma membrane] [Complex:R-CEL-74693] PI3K [cytosol] [Complex:R-CEL-1306961] EGF:p-EGFR:p-ERBB2:GRB2:GAB1:PI3K [plasma membrane]
(input)	[Reaction:R-CEL-5654640] Activated FGFR3:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA [Reaction:R-CEL-5654614] Activated FGFR2:p-FRS2:GRB2:GAB1:PI3KR1 binds PIK3CA
(inferredTo)	[DefinedSet:R-HSA-74689] PI3K-catalytic subunit [cytosol] [EntityWithAccessionedSequence:R-HSA-74787] PIK3CA [cytosol]

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