Reactome | MEMO1 binds RHOA:GTP:DIAPH1

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MEMO1 binds RHOA:GTP:DIAPH1 Show undefined attributes

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10972265
displayName	MEMO1 binds RHOA:GTP:DIAPH1
eventOf	[Pathway:R-CEL-6785631] ERBB2 Regulates Cell Motility - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-6785648] MEMO1 binds RHOA:GTP:DIAPH1 - Homo sapiens
input	[Complex:R-CEL-6785640] p-ERBB2 heterodimers:MEMO1 [plasma membrane] [Complex:R-CEL-5665988] RHOA:GTP:DIAPH1 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	MEMO1 binds RHOA:GTP:DIAPH1
output	[Complex:R-CEL-6785647] p-ERBB2 heterodimers:MEMO1:RHOA:GTP:DIAPH1 [plasma membrane]
precedingEvent	[Reaction:R-CEL-6785636] Phosphorylated ERBB2 heterodimers bind MEMO1 - Caenorhabditis elegans [Reaction:R-CEL-5665989] DIAPH1 binds RHOA:GTP - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-6785648
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-6785631] ERBB2 Regulates Cell Motility
(inferredTo)	[Reaction:R-HSA-6785648] MEMO1 binds RHOA:GTP:DIAPH1