Reactome | ERBB2 Regulates Cell Motility

Schema > Pathway > Entries

created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10995615
displayName	ERBB2 Regulates Cell Motility
eventOf	[Pathway:R-CEL-1227986] Signaling by ERBB2 - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:1043045] regulation of cell motility
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-CEL-6785636] Phosphorylated ERBB2 heterodimers bind MEMO1 - Caenorhabditis elegans [Reaction:R-CEL-6785648] MEMO1 binds RHOA:GTP:DIAPH1 - Caenorhabditis elegans
inferredFrom	[Pathway:R-HSA-6785631] ERBB2 Regulates Cell Motility - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	ERBB2 Regulates Cell Motility
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-6785631
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CEL-1227986] Signaling by ERBB2
(inferredTo)	[Pathway:R-HSA-6785631] ERBB2 Regulates Cell Motility

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