Reactome | DIAPH1 binds RHOA:GTP

Schema > Reaction > Entries

category	binding
compartment	[Compartment:70101] cytosol [Compartment:876] plasma membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10967942
displayName	DIAPH1 binds RHOA:GTP
eventOf	[Pathway:R-CEL-5663220] RHO GTPases Activate Formins - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-6785648] MEMO1 binds RHOA:GTP:DIAPH1 - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-5665989] DIAPH1 binds RHOA:GTP - Homo sapiens
input	[Complex:R-CEL-5665967] DIAPH1 [cytosol] [Complex:R-CEL-5665993] RHOA:GTP [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	DIAPH1 binds RHOA:GTP
output	[Complex:R-CEL-5665988] RHOA:GTP:DIAPH1 [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-5665989
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-CEL-5663220] RHO GTPases Activate Formins
(precedingEvent)	[Reaction:R-CEL-6785648] MEMO1 binds RHOA:GTP:DIAPH1
(inferredTo)	[Reaction:R-HSA-5665989] DIAPH1 binds RHOA:GTP

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