Reactome | ERCC2-facilitated RNA Pol II backtracking in TC-NER

Schema > Reaction > Entries

ERCC2-facilitated RNA Pol II backtracking in TC-NER Show undefined attributes

catalystActivity	[CatalystActivity:10971981] 5'-3' DNA helicase activity of TC-NER pre-incision complex [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10971983
displayName	ERCC2-facilitated RNA Pol II backtracking in TC-NER
eventOf	[Pathway:R-CEL-6782135] Dual incision in TC-NER - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-9684118] ERCC3-facilitated RNA Pol II backtracking in TC-NER - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-6782131] ERCC2-facilitated RNA Pol II backtracking in TC-NER - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-CEL-6782066] TC-NER pre-incision complex [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	ERCC2-facilitated RNA Pol II backtracking in TC-NER
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [SimpleEntity:R-ALL-113550] Pi [nucleoplasm] [Complex:R-CEL-9684117] TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm]
precedingEvent	[Reaction:R-CEL-6782069] UVSSA:USP7 deubiquitinates ERCC6 - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-6782131
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-6782135] Dual incision in TC-NER
(precedingEvent)	[Reaction:R-CEL-9684118] ERCC3-facilitated RNA Pol II backtracking in TC-NER
(inferredTo)	[Reaction:R-HSA-6782131] ERCC2-facilitated RNA Pol II backtracking in TC-NER

Cite Us!