Reactome | CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible)

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CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) Show undefined attributes

catalystActivity	[CatalystActivity:10948664] 1-acylglycerol-3-phosphate O-acyltransferase activity of TAZ [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10948666
displayName	CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible)
eventOf	[Pathway:R-CEL-1482798] Acyl chain remodeling of CL - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-1482775] MLCL is acylated to CL by HADH (IM) - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) - Homo sapiens
input	[SimpleEntity:R-ALL-1524089] 1-acyl LPE [mitochondrial inner membrane] [SimpleEntity:R-ALL-1524072] cardiolipin [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible)
output	[SimpleEntity:R-ALL-1498773] MLCL [mitochondrial inner membrane] [SimpleEntity:R-ALL-1524083] PE [mitochondrial inner membrane]
precedingEvent	[Reaction:R-CEL-1483063] PG and CDP-DAG are converted to CL by CRLS1 - Caenorhabditis elegans [Reaction:R-CEL-1482775] MLCL is acylated to CL by HADH (IM) - Caenorhabditis elegans [Reaction:R-CEL-1482781] MLCL and PC are converted to CL and 1-acyl LPC by TAZ (IM) (Reversible) - Caenorhabditis elegans [Reaction:R-CEL-1482850] MLCL and PE are converted to CL and 1-acyl LPE by TAZ (IM) (Reversible) - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-1482894
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-1482798] Acyl chain remodeling of CL
(precedingEvent)	[Reaction:R-CEL-1482775] MLCL is acylated to CL by HADH (IM)
(inferredTo)	[Reaction:R-HSA-1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible)

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