Reactome | MLCL is acylated to CL by HADH (IM)

Schema > Reaction > Entries

MLCL is acylated to CL by HADH (IM) Show undefined attributes

catalystActivity	[CatalystActivity:10948606] O-acyltransferase activity of HADH octamer [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10948608
displayName	MLCL is acylated to CL by HADH (IM)
eventOf	[Pathway:R-CEL-1482798] Acyl chain remodeling of CL - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-1482794] CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) - Caenorhabditis elegans [Reaction:R-CEL-1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-1482775] MLCL is acylated to CL by HADH (IM) - Homo sapiens
input	[SimpleEntity:R-ALL-1524038] acyl-CoA [mitochondrial matrix] [SimpleEntity:R-ALL-1498773] MLCL [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	MLCL is acylated to CL by HADH (IM)
output	[SimpleEntity:R-ALL-1524072] cardiolipin [mitochondrial inner membrane] [SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix]
precedingEvent	[Reaction:R-CEL-1482794] CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) - Caenorhabditis elegans [Reaction:R-CEL-1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-1482775
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-1482798] Acyl chain remodeling of CL
(precedingEvent)	[Reaction:R-CEL-1482794] CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) [Reaction:R-CEL-1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible)
(inferredTo)	[Reaction:R-HSA-1482775] MLCL is acylated to CL by HADH (IM)