Reactome | PG and CDP-DAG are converted to CL by CRLS1

Schema > Reaction > Entries

PG and CDP-DAG are converted to CL by CRLS1 Show undefined attributes

catalystActivity	[CatalystActivity:10948767] cardiolipin synthase (CMP-forming) activity of CRLS1 [mitochondrial inner membrane]
category	transition
compartment	[Compartment:70616] mitochondrial inner membrane [Compartment:5460] mitochondrial matrix
created	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
dbId	10948769
displayName	PG and CDP-DAG are converted to CL by CRLS1
eventOf	[Pathway:R-CEL-1483076] Synthesis of CL - Caenorhabditis elegans
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-CEL-1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) - Caenorhabditis elegans [Reaction:R-CEL-1482794] CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible) - Caenorhabditis elegans
inferredFrom	[Reaction:R-HSA-1483063] PG and CDP-DAG are converted to CL by CRLS1 - Homo sapiens
input	[SimpleEntity:R-ALL-1524064] CDP-DAG [mitochondrial inner membrane] [SimpleEntity:R-ALL-1524042] PG [mitochondrial inner membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	PG and CDP-DAG are converted to CL by CRLS1
output	[SimpleEntity:R-ALL-1524072] cardiolipin [mitochondrial inner membrane] [SimpleEntity:R-ALL-1524067] CMP [mitochondrial matrix]
precedingEvent	[Reaction:R-CEL-1483165] PA is converted to CDP-DAG by CDS2 - Caenorhabditis elegans
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68320] Caenorhabditis elegans
stId	R-CEL-1483063
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-CEL-1483076] Synthesis of CL
(precedingEvent)	[Reaction:R-CEL-1482894] CL and 1-acyl LPE are converted to MLCL and PE by TAZ (IM) (Reversible) [Reaction:R-CEL-1482794] CL and 1-acyl LPC are converted to MLCL and PC by TAZ (IM) (Reversible)
(inferredTo)	[Reaction:R-HSA-1483063] PG and CDP-DAG are converted to CL by CRLS1