Reactome | BoNT/E HC:LC dimer [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-5244512] botE:SV2:GT1b [plasma membrane] - Homo sapiens
created	[InstanceEdit:5228949] D'Eustachio, Peter, 2014-01-14
crossReference	[DatabaseIdentifier:12020820] Mondo:0005498
dbId	5228955
deleted	[Deleted:5251007] Deletion of instance: 181495
disease	[Disease:3632909] botulism
displayName	BoNT/E HC:LC dimer [plasma membrane]
goCellularComponent	[GO_CellularComponent:6485] host cell plasma membrane
hasComponent	[Complex:R-CBO-190051] BoNT/E LC:Zn2+ disulfide bonded [plasma membrane] [EntityWithAccessionedSequence:R-CBO-181571] botE HC disulfide bonded [plasma membrane]
inDisease	true
isChimeric	false
literatureReference	[LiteratureReference:5228677] Botulinum neurotoxin type E fragmented with endoproteinase Lys-C reveals the site trypsin nicks and homology with tetanus neurotoxin
maxDepth	3
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	BoNT/E HC:LC dimer
schemaClass	Complex
species	[Species:168825] Clostridium botulinum
stId	R-CBO-5228955

(replacementInstances)	[Deleted:5251007] Deletion of instance: 181495
(hasComponent)	[Complex:R-HSA-5244512] botE:SV2:GT1b [plasma membrane]

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