Reactome | BoNT/E LC:Zn2+ disulfide bonded [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-CBO-5228955] BoNT/E HC:LC dimer [plasma membrane] - Clostridium botulinum
created	[InstanceEdit:190033] Gopinathrao, G, 2006-12-13 17:03:37
crossReference	[DatabaseIdentifier:12020820] Mondo:0005498
dbId	190051
deleted	[Deleted:5251009] Deletion of instance: 168796
disease	[Disease:3632909] botulism
displayName	BoNT/E LC:Zn2+ disulfide bonded [plasma membrane]
goCellularComponent	[GO_CellularComponent:6485] host cell plasma membrane
hasComponent	[EntityWithAccessionedSequence:R-CBO-181476] botE LC disulfide bonded [plasma membrane] [SimpleEntity:R-ALL-109265] Zn2+ [plasma membrane]
inDisease	true
literatureReference	[LiteratureReference:5228676] Structural analysis of botulinum neurotoxin type E catalytic domain and its mutant Glu212-->Gln reveals the pivotal role of the Glu212 carboxylate in the catalytic pathway
maxDepth	2
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
name	BoNT/E LC:Zn2+ disulfide bonded BoNT Light chain Type E
schemaClass	Complex
species	[Species:168825] Clostridium botulinum
stId	R-CBO-190051
updateTrackers	[UpdateTracker:9889038] Update Tracker - [Complex:190051] BoNT/E LC:Zn2+ disulfide bonded [plasma membrane] - v48:[addDisease, addLiteratureReference, addName]

(updatedInstance)	[UpdateTracker:9889038] Update Tracker - [Complex:190051] BoNT/E LC:Zn2+ disulfide bonded [plasma membrane] - v48:[addDisease, addLiteratureReference, addName]
(replacementInstances)	[Deleted:5251009] Deletion of instance: 168796
(hasComponent)	[Complex:R-CBO-5228955] BoNT/E HC:LC dimer [plasma membrane]

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