Reactome | The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA

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The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA Show undefined attributes

catalystActivity	[CatalystActivity:10441523] 3'-5'-RNA exonuclease activity of RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA [nucleoplasm]
category	omitted
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10441525
displayName	The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA
eventOf	[Pathway:R-BTA-9930044] Nuclear RNA decay - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-9934763] The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA - Homo sapiens
input	[Complex:R-BTA-9934534] RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA
output	[Complex:R-BTA-9930043] CBCA complex [nucleoplasm] [Complex:R-BTA-9935998] NEXT homodimer [nucleoplasm] [Complex:R-BTA-9933578] RNA exosome [nucleoplasm] [EntityWithAccessionedSequence:R-BTA-9930040] ZC3H18 [nucleoplasm]
precedingEvent	[Reaction:R-BTA-9934522] NEXT:ZC3H18:CBCA:m7GpppN-RNA binds the RNA exosome - Bos taurus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-9934763
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9930044] Nuclear RNA decay
(inferredTo)	[BlackBoxEvent:R-HSA-9934763] The RNA exosome in RNA exosome:NEXT:ZC3H18:CBCA:m7GpppN-RNA hydrolyzes RNA

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