Reactome | TFPI? + FV intermediate + PROS1 => TFPI?:FV intermediate:PROS1

Schema > Reaction > Entries

TFPI? + FV intermediate + PROS1 => TFPI?:FV intermediate:PROS1 Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10441131
displayName	TFPI? + FV intermediate + PROS1 => TFPI?:FV intermediate:PROS1
eventOf	[Pathway:R-BTA-9769739] Regulation of clotting cascade - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-9931628] TFPI? + FV intermediate + PROS1 => TFPI?:FV intermediate:PROS1 - Homo sapiens
input	[Complex:R-BTA-9930795] factor Va intermediate [extracellular region] [EntityWithAccessionedSequence:R-BTA-202772] PROS1 [extracellular region] [EntityWithAccessionedSequence:R-BTA-9931632] TFPI [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	TFPI? + FV intermediate + PROS1 => TFPI?:FV intermediate:PROS1 TFPI? binds FV intermediate and protein S
output	[Complex:R-BTA-9931610] TFPI?:FV intermediate:PROS1 [extracellular region]
precedingEvent	[Reaction:R-BTA-9769737] factor V -> factor Va intermediate + factor V activation peptide (FXa catalyst) - Bos taurus [Reaction:R-BTA-9930790] factor V -> factor Va intermediate + factor V activation peptide (thrombin catalyst) - Bos taurus [Reaction:R-BTA-481007] Exocytosis of platelet alpha granule contents - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-9931628
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9769739] Regulation of clotting cascade
(inferredTo)	[Reaction:R-HSA-9931628] TFPI? + FV intermediate + PROS1 => TFPI?:FV intermediate:PROS1

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