Reactome | STAT1,STAT3 associate with IL27RA:IL12RB2 receptor

Schema > BlackBoxEvent > Entries

STAT1,STAT3 associate with IL27RA:IL12RB2 receptor Show undefined attributes

category	omitted
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10429297
displayName	STAT1,STAT3 associate with IL27RA:IL12RB2 receptor
eventOf	[Pathway:R-BTA-8984722] Interleukin-35 Signalling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-BTA-8984014] JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 - Bos taurus
inferredFrom	[BlackBoxEvent:R-HSA-8984021] STAT1,STAT3 associate with IL27RA:IL12RB2 receptor - Homo sapiens
input	[Complex:R-BTA-8985392] IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2 [plasma membrane] [EntityWithAccessionedSequence:R-BTA-629622] STAT1 [cytosol] [EntityWithAccessionedSequence:R-BTA-539044] STAT3 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	STAT1,STAT3 associate with IL27RA:IL12RB2 receptor
output	[Complex:R-BTA-8983998] IL35:IL27RA:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT3 [plasma membrane]
precedingEvent	[BlackBoxEvent:R-BTA-8984012] JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated - Bos taurus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-8984021
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-8984722] Interleukin-35 Signalling
(precedingEvent)	[BlackBoxEvent:R-BTA-8984014] JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3
(inferredTo)	[BlackBoxEvent:R-HSA-8984021] STAT1,STAT3 associate with IL27RA:IL12RB2 receptor

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