Reactome | STAT1 associates with IL6ST:IL6ST

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STAT1 associates with IL6ST:IL6ST Show undefined attributes

category	omitted
compartment	[Compartment:876] plasma membrane [Compartment:70101] cytosol [Compartment:984] extracellular region
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10429258
displayName	STAT1 associates with IL6ST:IL6ST
eventOf	[Pathway:R-BTA-8984722] Interleukin-35 Signalling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-BTA-8983835] JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 - Bos taurus
inferredFrom	[BlackBoxEvent:R-HSA-8983841] STAT1 associates with IL6ST:IL6ST - Homo sapiens
input	[Complex:R-BTA-8983843] IL-35:(IL6ST:p-JAK1:p-JAK2) dimer [plasma membrane] [EntityWithAccessionedSequence:R-BTA-629622] STAT1 [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	STAT1 associates with IL6ST:IL6ST
output	[Complex:R-BTA-8983842] IL-35:(IL6ST:p-JAK1:p-JAK2) dimer: STAT1 [plasma membrane]
precedingEvent	[BlackBoxEvent:R-BTA-8983834] JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated - Bos taurus
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-8983841
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-8984722] Interleukin-35 Signalling
(precedingEvent)	[BlackBoxEvent:R-BTA-8983835] JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1
(inferredTo)	[BlackBoxEvent:R-HSA-8983841] STAT1 associates with IL6ST:IL6ST

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