Reactome | RUNX3 regulates p14-ARF

Schema > Pathway > Entries

created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10445934
displayName	RUNX3 regulates p14-ARF
eventOf	[Pathway:R-BTA-8878159] Transcriptional regulation by RUNX3 - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-8951951] RUNX3 binds EP300 - Bos taurus [Reaction:R-BTA-8951966] EP300 acetylates RUNX3 - Bos taurus [Reaction:R-BTA-8952058] CCND1 binds RUNX3 and displaces EP300 - Bos taurus [Reaction:R-BTA-8952062] CCND1 recruits HDAC4 to RUNX3 - Bos taurus
inferredFrom	[Pathway:R-HSA-8951936] RUNX3 regulates p14-ARF - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	2
name	RUNX3 regulates p14-ARF
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-8951936
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-8878159] Transcriptional regulation by RUNX3
(inferredTo)	[Pathway:R-HSA-8951936] RUNX3 regulates p14-ARF