Reactome | CCND1 binds RUNX3 and displaces EP300

Schema > Reaction > Entries

CCND1 binds RUNX3 and displaces EP300 Show undefined attributes

category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10427225
displayName	CCND1 binds RUNX3 and displaces EP300
eventOf	[Pathway:R-BTA-8951936] RUNX3 regulates p14-ARF - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-8952062] CCND1 recruits HDAC4 to RUNX3 - Bos taurus
inferredFrom	[Reaction:R-HSA-8952058] CCND1 binds RUNX3 and displaces EP300 - Homo sapiens
input	[Complex:R-BTA-8951976] Ac-K94,K171-RUNX3:CBFB:EP300:BRD2 [nucleoplasm] [EntityWithAccessionedSequence:R-BTA-113832] CCND1 [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	CCND1 binds RUNX3 and displaces EP300
output	[Complex:R-BTA-8952057] Ac-K94,K171-RUNX3:CBFB:BRD2:CCND1 [nucleoplasm] [EntityWithAccessionedSequence:R-BTA-381325] EP300 [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-8952058
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-8951936] RUNX3 regulates p14-ARF
(precedingEvent)	[Reaction:R-BTA-8952062] CCND1 recruits HDAC4 to RUNX3
(inferredTo)	[Reaction:R-HSA-8952058] CCND1 binds RUNX3 and displaces EP300

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