Reactome | Recognition and binding of the mRNA cap by the cap-binding complex

Schema > Reaction > Entries

Recognition and binding of the mRNA cap by the cap-binding complex Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10339090
displayName	Recognition and binding of the mRNA cap by the cap-binding complex
eventOf	[Pathway:R-BTA-72086] mRNA Capping - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-72095] Internal Methylation of mRNA - Bos taurus [Reaction:R-BTA-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein - Bos taurus [Reaction:R-BTA-77589] Recognition of AAUAAA sequence by CPSF - Bos taurus [Reaction:R-BTA-77584] Binding of SLBP to Replication-Dependent Histone Pre-mRNA - Bos taurus [Reaction:R-BTA-111438] Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA - Bos taurus
inferredFrom	[Reaction:R-HSA-77095] Recognition and binding of the mRNA cap by the cap-binding complex - Homo sapiens
input	[Complex:R-BTA-77088] Cap Binding Complex (CBC) [nucleoplasm] [Complex:R-BTA-113405] RNA Polymerase II (phosphorylated):TFIIF:capped pre-mRNA [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	Recognition and binding of the mRNA cap by the cap-binding complex
output	[Complex:R-BTA-77089] capped pre-mRNA:CBC:RNA Pol II (phosphorylated) complex [nucleoplasm]
precedingEvent	[Reaction:R-BTA-77090] Methylation of GMP-cap by RNA Methyltransferase - Bos taurus [Reaction:R-BTA-77094] Formation of cap binding complex (CBC) - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-77095
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-72086] mRNA Capping
(precedingEvent)	[Reaction:R-BTA-72095] Internal Methylation of mRNA [Reaction:R-BTA-112383] Hypophosphorylation of RNA Pol II CTD by FCP1P protein [Reaction:R-BTA-77589] Recognition of AAUAAA sequence by CPSF [Reaction:R-BTA-77584] Binding of SLBP to Replication-Dependent Histone Pre-mRNA [Reaction:R-BTA-111438] Recruitment of U7 snRNP:ZFP100 complex to the Histone Pre-mRNA
(inferredTo)	[Reaction:R-HSA-77095] Recognition and binding of the mRNA cap by the cap-binding complex