Reactome | MLKL [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-BTA-5218909] (RIPK1:RIPK3)oligomer:4xMLKL [cytosol] - Bos taurus [Complex:R-BTA-5218909] (RIPK1:RIPK3)oligomer:4xMLKL [cytosol] - Bos taurus [Complex:R-BTA-5218909] (RIPK1:RIPK3)oligomer:4xMLKL [cytosol] - Bos taurus [Complex:R-BTA-5218909] (RIPK1:RIPK3)oligomer:4xMLKL [cytosol] - Bos taurus [Complex:R-BTA-9687642] MLKL:ATP [cytosol] - Bos taurus [Complex:R-BTA-9698842] MLKL:HSP90:CDC37 [cytosol] - Bos taurus
consumedByEvent	[Reaction:R-BTA-5218891] RIPK1:RIPK3 oligomer binds MLKL - Bos taurus [Reaction:R-BTA-5218891] RIPK1:RIPK3 oligomer binds MLKL - Bos taurus [Reaction:R-BTA-5218891] RIPK1:RIPK3 oligomer binds MLKL - Bos taurus [Reaction:R-BTA-5218891] RIPK1:RIPK3 oligomer binds MLKL - Bos taurus [Reaction:R-BTA-9698844] MLKL binds HSP90:CDC37 - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10398172
displayName	MLKL [cytosol]
endCoordinate	471
inDisease	false
inferredFrom	[EntityWithAccessionedSequence:R-HSA-5218901] MLKL [cytosol] - Homo sapiens
maxDepth	1
name	MLKL MLKL E1BGC6
referenceEntity	[ReferenceGeneProduct:uniprot:E1BGC6] UniProt:E1BGC6
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48898] Bos taurus
stId	R-BTA-5218901
startCoordinate	1

(input)	[Reaction:R-BTA-9698844] MLKL binds HSP90:CDC37 [Reaction:R-BTA-5218891] RIPK1:RIPK3 oligomer binds MLKL
(hasComponent)	[Complex:R-BTA-9698842] MLKL:HSP90:CDC37 [cytosol] [Complex:R-BTA-9687642] MLKL:ATP [cytosol] [Complex:R-BTA-5218909] (RIPK1:RIPK3)oligomer:4xMLKL [cytosol]
(inferredTo)	[EntityWithAccessionedSequence:R-HSA-5218901] MLKL [cytosol]