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MLKL [cytosol]
Stable Identifier
R-BTA-5218901
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
cytosol
Synonyms
MLKL, E1BGC6
Locations in the PathwayBrowser
Expand all
Programmed Cell Death (Bos taurus)
Regulated Necrosis (Bos taurus)
RIPK1-mediated regulated necrosis (Bos taurus)
RIPK1:RIPK3 oligomer binds MLKL (Bos taurus)
(RIPK1:RIPK3)oligomer:4xMLKL [cytosol] (Bos taurus)
MLKL [cytosol] (Bos taurus)
MLKL [cytosol] (Bos taurus)
RIPK3 phosphorylates MLKL (Bos taurus)
(RIPK1:RIPK3)oligomer:4xMLKL [cytosol] (Bos taurus)
MLKL [cytosol] (Bos taurus)
Regulation of necroptotic cell death (Bos taurus)
ATP binds MLKL (Bos taurus)
(RIPK1:RIPK3)oligomer:4xMLKL [cytosol] (Bos taurus)
MLKL [cytosol] (Bos taurus)
(p-S-RIPK1:p-S199,227-RIPK3) oligomer:4x(MLKL:ATP) [cytosol] (Bos taurus)
MLKL:ATP [cytosol] (Bos taurus)
MLKL [cytosol] (Bos taurus)
MLKL binds HSP90:CDC37 (Bos taurus)
MLKL [cytosol] (Bos taurus)
MLKL:HSP90:CDC37 [cytosol] (Bos taurus)
MLKL [cytosol] (Bos taurus)
External Reference Information
External Reference
UniProt:E1BGC6
Gene Names
MLKL
Reference Genes
BioGPS Gene:790225 MLKL
ENSEMBL:ENSBTAG00000012216.6
KEGG:bta:790225 MLKL
Monarch:790225 MLKL
NCBI Gene:790225 MLKL
UCSC:E1BGC6 MLKL
Reference Transcript
RefSeq:XM_002694707.7 MLKL
Other Identifiers
790225
Bt.20017.1.S1_at
Bt.25448.1.A1_at
Bt.27239.1.A1_at
GO:0003824
GO:0004672
GO:0005524
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006468
GO:0007166
GO:0016740
GO:0019901
GO:0030054
GO:0044877
GO:0051607
GO:0070207
GO:0070266
GO:0097527
GO:0097528
GO:0098542
GO:0140096
Participates
as an input of
MLKL binds HSP90:CDC37 (Bos taurus)
RIPK1:RIPK3 oligomer binds MLKL (Bos taurus)
as a component of
MLKL:HSP90:CDC37 [cytosol] (Bos taurus)
MLKL:ATP [cytosol] (Bos taurus)
(RIPK1:RIPK3)oligomer:4xMLKL [cytosol] (Bos taurus)
Other forms of this molecule
phospho-MLKL [cytosol]
phospho-MLKL [cytosol]
Inferred From
MLKL [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_002694753.1
ENSEMBL
ENSBTAP00000016202
,
ENSBTAG00000012216
,
ENSBTAT00000016202
VGNC
31500
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