Reactome | TLE oligomerizes

Schema > Reaction > Entries

category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10396450
displayName	TLE oligomerizes
eventOf	[Pathway:R-BTA-4641265] Repression of WNT target genes - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-8944349] TLE tetramers bind TCF/LEF at WNT promoters - Bos taurus
inferredFrom	[Reaction:R-HSA-4641229] TLE oligomerizes - Homo sapiens
input	4 × [DefinedSet:R-BTA-4649011] TLE [nucleoplasm]
isInDisease	false
isInferred	true
maxDepth	1
name	TLE oligomerizes
output	[DefinedSet:R-BTA-3299565] TLE tetramer [nucleoplasm]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-4641229
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-BTA-4641265] Repression of WNT target genes
(precedingEvent)	[Reaction:R-BTA-8944349] TLE tetramers bind TCF/LEF at WNT promoters
(inferredTo)	[Reaction:R-HSA-4641229] TLE oligomerizes

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