Reactome | IL27:EBI3 [extracellular region]

Schema > Complex > Entries

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-BTA-8952746] p-Y701-STAT1:p-Y705-STAT3:IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] - Bos taurus [Complex:R-BTA-8950331] IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] - Bos taurus
consumedByEvent	[Reaction:R-BTA-448427] Interleukin-27 binds Interleukin-27 receptor - Bos taurus
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10365864
displayName	IL27:EBI3 [extracellular region]
hasComponent	[EntityWithAccessionedSequence:R-BTA-448418] EBI3 [extracellular region] [EntityWithAccessionedSequence:R-BTA-448466] IL27 [extracellular region]
inDisease	false
inferredFrom	[Complex:R-HSA-448442] IL27:EBI3 [extracellular region] - Homo sapiens
maxDepth	2
name	IL27:EBI3
producedByEvent	[Reaction:R-BTA-8950210] Interleukin-27 dissociates from Interleukin-27 receptor - Bos taurus [BlackBoxEvent:R-BTA-448421] Interleukin-27 translocates from the ER lumen to the extracellular region - Bos taurus
schemaClass	Complex
species	[Species:48898] Bos taurus
stId	R-BTA-448442
summation	[Summation:9984903] This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

(input)	[Reaction:R-BTA-448427] Interleukin-27 binds Interleukin-27 receptor
(output)	[Reaction:R-BTA-8950210] Interleukin-27 dissociates from Interleukin-27 receptor [BlackBoxEvent:R-BTA-448421] Interleukin-27 translocates from the ER lumen to the extracellular region
(hasComponent)	[Complex:R-BTA-8950331] IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] [Complex:R-BTA-8952746] p-Y701-STAT1:p-Y705-STAT3:IL27:EBI3:p-Y611-IL27RA:p-JAK1:p-Y-IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] [Complex:R-BTA-8950252] IL27:EBI3:IL27RA:p-JAK1:IL6ST:p-JAK1,p-JAK2,p-TYK2 [plasma membrane] [Complex:R-BTA-448431] IL27:EBI3:IL27RA:JAK1:IL6ST:JAK1,JAK2,(TYK2) [plasma membrane]
(inferredTo)	[Complex:R-HSA-448442] IL27:EBI3 [extracellular region]

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