Reactome | Interleukin-27 translocates from the ER lumen to the extracellular region

Schema > BlackBoxEvent > Entries

Interleukin-27 translocates from the ER lumen to the extracellular region Show undefined attributes

category	omitted
compartment	[Compartment:984] extracellular region [Compartment:17957] endoplasmic reticulum lumen
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10365866
displayName	Interleukin-27 translocates from the ER lumen to the extracellular region
eventOf	[Pathway:R-BTA-9020956] Interleukin-27 signaling - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[BlackBoxEvent:R-HSA-448421] Interleukin-27 translocates from the ER lumen to the extracellular region - Homo sapiens
input	[Complex:R-BTA-8950372] IL27:EBI3 [endoplasmic reticulum lumen]
isInDisease	false
isInferred	true
maxDepth	1
name	Interleukin-27 translocates from the ER lumen to the extracellular region IL27:EBI3 (IL27) is secreted to the extracellular space
output	[Complex:R-BTA-448442] IL27:EBI3 [extracellular region]
releaseDate	2026-03-25
schemaClass	BlackBoxEvent
species	[Species:48898] Bos taurus
stId	R-BTA-448421
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9020956] Interleukin-27 signaling
(inferredTo)	[BlackBoxEvent:R-HSA-448421] Interleukin-27 translocates from the ER lumen to the extracellular region

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