Reactome | Mevalonate-5-phosphate is further phosphorylated

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Mevalonate-5-phosphate is further phosphorylated Show undefined attributes

catalystActivity	[CatalystActivity:10348832] phosphomevalonate kinase activity of PMVK [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10332713] Weiser, Joel, 2026-03-16
dbId	10348834
displayName	Mevalonate-5-phosphate is further phosphorylated
eventOf	[Pathway:R-BTA-9969896] Lanosterol biosynthesis - Bos taurus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-BTA-191414] MVD decarboxylates MVA5PP to IPPP - Bos taurus
inferredFrom	[Reaction:R-HSA-191422] Mevalonate-5-phosphate is further phosphorylated - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-191296] MVA5P [cytosol]
isInDisease	false
isInferred	true
maxDepth	1
name	Mevalonate-5-phosphate is further phosphorylated (R)-5-phosphomevalonate + ATP => (R)-5-diphosphomevalonate + ADP
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-191403] MVA5PP [cytosol]
precedingEvent	[Reaction:R-BTA-191380] Mevalonate is phosphorylated to mevalonate-5-phosphate - Bos taurus
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48898] Bos taurus
stId	R-BTA-191422
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-9969896] Lanosterol biosynthesis
(precedingEvent)	[Reaction:R-BTA-191414] MVD decarboxylates MVA5PP to IPPP
(inferredTo)	[Reaction:R-HSA-191422] Mevalonate-5-phosphate is further phosphorylated

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