Reactome | Mevalonate-5-phosphate is further phosphorylated

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Mevalonate-5-phosphate is further phosphorylated Show undefined attributes

authored	[InstanceEdit:191754] Jassal, B, 2007-01-24 15:15:12
catalystActivity	[CatalystActivity:191287] phosphomevalonate kinase activity of PMVK [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:191331] Jassal, Bijay, 2007-01-19
crossReference	[DatabaseIdentifier:12667846] RHEA:16342 [DatabaseIdentifier:9945094] RHEA:16342
dbId	191422
displayName	Mevalonate-5-phosphate is further phosphorylated
eventOf	[Pathway:R-HSA-9969896] Lanosterol biosynthesis - Homo sapiens
followingEvent	[Reaction:R-HSA-191414] MVD decarboxylates MVA5PP to IPPP - Homo sapiens
input	[SimpleEntity:R-ALL-113592] ATP [cytosol] [SimpleEntity:R-ALL-191296] MVA5P [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:191392] Phosphomevalonate kinase: functional investigation of the recombinant human enzyme [LiteratureReference:191291] Phosphomevalonate kinase is a cytosolic protein in humans
maxDepth	1
modified	[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name	Mevalonate-5-phosphate is further phosphorylated (R)-5-phosphomevalonate + ATP => (R)-5-diphosphomevalonate + ADP
orthologousEvent	[Reaction:R-CEL-191422] Mevalonate-5-phosphate is further phosphorylated - Caenorhabditis elegans [Reaction:R-DME-191422] Mevalonate-5-phosphate is further phosphorylated - Drosophila melanogaster [Reaction:R-GGA-191422] Mevalonate-5-phosphate is further phosphorylated - Gallus gallus [Reaction:R-DRE-191422] Mevalonate-5-phosphate is further phosphorylated - Danio rerio [Reaction:R-SSC-191422] Mevalonate-5-phosphate is further phosphorylated - Sus scrofa [Reaction:R-BTA-191422] Mevalonate-5-phosphate is further phosphorylated - Bos taurus [Reaction:R-CFA-191422] Mevalonate-5-phosphate is further phosphorylated - Canis familiaris [Reaction:R-RNO-191422] Mevalonate-5-phosphate is further phosphorylated - Rattus norvegicus [Reaction:R-MMU-191422] Mevalonate-5-phosphate is further phosphorylated - Mus musculus
output	[SimpleEntity:R-ALL-29370] ADP [cytosol] [SimpleEntity:R-ALL-191403] MVA5PP [cytosol]
precedingEvent	[Reaction:R-HSA-191380] Mevalonate is phosphorylated to mevalonate-5-phosphate - Homo sapiens
releaseDate	2007-02-20
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:191591] D'Eustachio, P, 2007-01-22 01:32:07
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-191422
summation	[Summation:191335] Cytosolic phosphomevalonate kinase (PMK) catalyzes the rever...
updateTrackers	[UpdateTracker:9971929] Update Tracker - [Reaction:191422] Mevalonate-5-phosphate is further phosphorylated - v95:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9971929] Update Tracker - [Reaction:191422] Mevalonate-5-phosphate is further phosphorylated - v95:[modifyText]
(hasEvent)	[Pathway:R-HSA-9969896] Lanosterol biosynthesis
(precedingEvent)	[Reaction:R-HSA-191414] MVD decarboxylates MVA5PP to IPPP

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