Reactome | pexidartinib [cytosol]

Schema > ChemicalDrug > Entries

compartment	[Compartment:70101] cytosol
consumedByEvent	[FailedReaction:R-HSA-9702607] pexidartinib-resistant FLT3 mutants don't bind pexidartinib - Homo sapiens
created	[InstanceEdit:9677648] Rothfels, Karen, 2020-03-09
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992 [DatabaseIdentifier:9677644] ChEBI:145373
dbId	9677649
disease	[Disease:1500689] cancer
displayName	pexidartinib [cytosol]
inDisease	true
maxDepth	1
memberOf	[DefinedSet:R-ALL-9695783] type II FLT3-binding TKIs [cytosol]
name	pexidartinib PLX3397 PLX-3397 Turalio®
referenceEntity	[ReferenceTherapeutic:iuphar.ligand:8710] pexidartinib [Guide to Pharmacology:8710]
schemaClass	ChemicalDrug
stId	R-ALL-9677649

(input)	[FailedReaction:R-HSA-9702607] pexidartinib-resistant FLT3 mutants don't bind pexidartinib
(hasMember)	[DefinedSet:R-ALL-9695783] type II FLT3-binding TKIs [cytosol]

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