Reactome | selumetinib [cytosol]

Schema > ChemicalDrug > Entries

candidateOf	[CandidateSet:R-ALL-9657574] single mechanism MAP2K1/2 inhibitors [cytosol]
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:9657509] Rothfels, Karen, 2019-08-08
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992 [DatabaseIdentifier:9657510] ChEBI:90227
dbId	9657511
disease	[Disease:1500689] cancer
displayName	selumetinib [cytosol]
inDisease	true
literatureReference	[LiteratureReference:9657446] Targeted inhibition of the extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) in the treatment of hepatocellular carcinoma [LiteratureReference:9657229] Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor
maxDepth	1
name	selumetinib
referenceEntity	[ReferenceTherapeutic:iuphar.ligand:5665] selumetinib [Guide to Pharmacology:5665]
schemaClass	ChemicalDrug
stId	R-ALL-9657511

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