selumetinib [cytosol]

Stable Identifier
R-ALL-9657511
Type
ChemicalDrug
Compartment
cytosol
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Literature References
PubMed ID Title Journal Year
17332304 Biological characterization of ARRY-142886 (AZD6244), a potent, highly selective mitogen-activated protein kinase kinase 1/2 inhibitor

Yeh, TC, Marsh, V, Bernat, BA, Ballard, J, Colwell, H, Evans, RJ, Parry, J, Smith, D, Brandhuber, BJ, Gross, S, Marlow, A, Hurley, B, Lyssikatos, J, Lee, PA, Winkler, JD, Koch, K, Wallace, E

Clin. Cancer Res. 2007
17237274 Targeted inhibition of the extracellular signal-regulated kinase kinase pathway with AZD6244 (ARRY-142886) in the treatment of hepatocellular carcinoma

Huynh, H, Soo, KC, Chow, PK, Tran, E

Mol. Cancer Ther. 2007
External Reference Information
External Reference
selumetinib [Guide to Pharmacology:5665]
Participates
as a candidate of
Disease
Name Identifier Synonyms
cancer DOID:162 malignant tumor, malignant neoplasm, primary cancer
Cross References
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ChEBI
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