Reactome | bMC-CoA [mitochondrial matrix]

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bMC-CoA [mitochondrial matrix] Show undefined attributes

compartment	[Compartment:5460] mitochondrial matrix
consumedByEvent	[FailedReaction:R-HSA-9909466] MCCC mutants don't synthesize beta-methylglutaconyl-CoA - Homo sapiens [Reaction:R-DDI-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Dictyostelium discoideum [Reaction:R-CEL-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Caenorhabditis elegans [Reaction:R-DME-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Drosophila melanogaster [Reaction:R-GGA-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Gallus gallus [Reaction:R-XTR-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Xenopus tropicalis [Reaction:R-SSC-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Sus scrofa [Reaction:R-BTA-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Bos taurus [Reaction:R-CFA-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Canis familiaris [Reaction:R-RNO-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Rattus norvegicus [Reaction:R-MMU-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Mus musculus [Reaction:R-HSA-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Homo sapiens [Reaction:R-DRE-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) - Danio rerio
crossReference	[DatabaseIdentifier:34122] COMPOUND:C03069
dbId	70744
displayName	bMC-CoA [mitochondrial matrix]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9760757] D'Eustachio, Peter, 2022-01-03
name	bMC-CoA beta-methylcrotonyl-CoA 3-methylbut-2-enoyl-CoA
producedByEvent	[Reaction:R-DDI-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Dictyostelium discoideum [Reaction:R-CEL-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Caenorhabditis elegans [Reaction:R-DME-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Drosophila melanogaster [Reaction:R-GGA-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Gallus gallus [Reaction:R-XTR-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Xenopus tropicalis [Reaction:R-DRE-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Danio rerio [Reaction:R-SSC-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Sus scrofa [Reaction:R-BTA-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Bos taurus [Reaction:R-CFA-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Canis familiaris [Reaction:R-RNO-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Rattus norvegicus [Reaction:R-MMU-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Mus musculus [Reaction:R-HSA-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) - Homo sapiens [Reaction:R-DDI-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Dictyostelium discoideum [Reaction:R-CEL-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Caenorhabditis elegans [Reaction:R-DME-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Drosophila melanogaster [Reaction:R-GGA-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Gallus gallus [Reaction:R-XTR-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Xenopus tropicalis [Reaction:R-SSC-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Sus scrofa [Reaction:R-BTA-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Bos taurus [Reaction:R-CFA-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Canis familiaris [Reaction:R-RNO-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Rattus norvegicus [Reaction:R-MMU-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Mus musculus [Reaction:R-HSA-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Homo sapiens [Reaction:R-DRE-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 - Danio rerio
referenceEntity	[ReferenceMolecule:chebi:57344] 3-methylbut-2-enoyl-CoA(4-) [ChEBI:57344]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-70744
updateTrackers	[UpdateTracker:9904128] Update Tracker - [SimpleEntity:70744] bMC-CoA [mitochondrial matrix] - v80:[add_removeReferenceEntity] [UpdateTracker:9873855] Update Tracker - [SimpleEntity:70744] bMC-CoA [mitochondrial matrix] - v43:[addName]

Referrals

(updatedInstance)	[UpdateTracker:9904128] Update Tracker - [SimpleEntity:70744] bMC-CoA [mitochondrial matrix] - v80:[add_removeReferenceEntity] [UpdateTracker:9873855] Update Tracker - [SimpleEntity:70744] bMC-CoA [mitochondrial matrix] - v43:[addName]
(input)	[FailedReaction:R-HSA-9909466] MCCC mutants don't synthesize beta-methylglutaconyl-CoA [Reaction:R-DDI-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) [Reaction:R-CEL-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) [Reaction:R-DME-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) [Reaction:R-GGA-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) [Reaction:R-XTR-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) [Reaction:R-SSC-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) [Reaction:R-BTA-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) [Reaction:R-CFA-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) [Reaction:R-RNO-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) [Reaction:R-MMU-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) [Reaction:R-HSA-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA) [Reaction:R-DRE-70773] beta-methylcrotonyl-CoA + ATP + HCO3- <=> beta-methylglutaconyl-CoA + ADP + orthophosphate + H2O (MCCA)
(output)	[Reaction:R-DDI-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-CEL-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-DME-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-GGA-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-XTR-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-DRE-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-SSC-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-BTA-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-CFA-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-RNO-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-MMU-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-HSA-508308] beta-methylglutaconyl-CoA + ADP + orthophosphate <=> beta-methylcrotonyl-CoA + ATP + HCO3- (MCCA) [Reaction:R-DDI-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Reaction:R-CEL-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Reaction:R-DME-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Reaction:R-GGA-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Reaction:R-XTR-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Reaction:R-SSC-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Reaction:R-BTA-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Reaction:R-CFA-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Reaction:R-RNO-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Reaction:R-MMU-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Reaction:R-HSA-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 [Reaction:R-DRE-70745] isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2

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