Reactome | mRNA Transcript Targeted by HuR Phosphorylated on Ser221 and Ser318 [nucleoplasm]

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mRNA Transcript Targeted by HuR Phosphorylated on Ser221 and Ser318 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-DME-517751] HuR with phosphoserine221 and phosphoserine318:mRNA Complex [nucleoplasm] - Drosophila melanogaster
consumedByEvent	[Reaction:R-DME-517705] p-S318,221-HuR binds mRNA - Drosophila melanogaster [Reaction:R-GGA-517705] p-S318,221-HuR binds mRNA - Gallus gallus [Reaction:R-DRE-517705] p-S318,221-HuR binds mRNA - Danio rerio [Reaction:R-SSC-517705] p-S318,221-HuR binds mRNA - Sus scrofa [Reaction:R-BTA-517705] p-S318,221-HuR binds mRNA - Bos taurus [Reaction:R-CFA-517705] p-S318,221-HuR binds mRNA - Canis familiaris [Reaction:R-RNO-517705] p-S318,221-HuR binds mRNA - Rattus norvegicus [Reaction:R-MMU-517705] p-S318,221-HuR binds mRNA - Mus musculus [Reaction:R-HSA-517705] p-S318,221-HuR binds mRNA - Homo sapiens
created	[InstanceEdit:517669] May, B, 2010-02-19
crossReference	[DatabaseIdentifier:427489] ChEBI:33697
dbId	517622
displayName	mRNA Transcript Targeted by HuR Phosphorylated on Ser221 and Ser318 [nucleoplasm]
inDisease	false
literatureReference	[LiteratureReference:517773] Tandem phosphorylation of serine 221 and 318 by PKC{delta} coordinates mRNA binding and nucleo-cytoplasmic shuttling of HuR [LiteratureReference:450594] Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA
maxDepth	1
modified	[InstanceEdit:9667254] D'Eustachio, Peter, 2019-11-08
name	mRNA Transcript Targeted by HuR Phosphorylated on Ser221 and Ser318
schemaClass	OtherEntity
stId	R-ALL-517622
summation	[Summation:561268] Phosphorylated HuR (phosphoserine221 and phosphoserine318) b...

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