Reactome | Hist [extracellular region]

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Hist [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
componentOf	[Complex:R-MMU-390881] HRH2:histamine [plasma membrane] - Mus musculus [Complex:R-DME-9692866] HRH3:Hist [plasma membrane] - Drosophila melanogaster
consumedByEvent	[Reaction:R-GGA-5696131] AOC1 deaminates Hist - Gallus gallus [Reaction:R-XTR-5696131] AOC1 deaminates Hist - Xenopus tropicalis [Reaction:R-DRE-5696131] AOC1 deaminates Hist - Danio rerio [Reaction:R-BTA-5696131] AOC1 deaminates Hist - Bos taurus [Reaction:R-RNO-5696131] AOC1 deaminates Hist - Rattus norvegicus [Reaction:R-MMU-5696131] AOC1 deaminates Hist - Mus musculus [Reaction:R-HSA-5696131] AOC1 deaminates Hist - Homo sapiens [Reaction:R-CEL-9692880] HRH3 binds Hist - Caenorhabditis elegans [Reaction:R-DME-9692880] HRH3 binds Hist - Drosophila melanogaster [Reaction:R-GGA-9692880] HRH3 binds Hist - Gallus gallus [Reaction:R-DRE-9692880] HRH3 binds Hist - Danio rerio [Reaction:R-SSC-9692880] HRH3 binds Hist - Sus scrofa [Reaction:R-BTA-9692880] HRH3 binds Hist - Bos taurus [Reaction:R-CFA-9692880] HRH3 binds Hist - Canis familiaris [Reaction:R-RNO-9692880] HRH3 binds Hist - Rattus norvegicus [Reaction:R-MMU-9692880] HRH3 binds Hist - Mus musculus [Reaction:R-HSA-9692880] HRH3 binds Hist - Homo sapiens [Reaction:R-HSA-390886] HRH4 binds Hist - Homo sapiens [Reaction:R-MMU-390886] HRH4 binds Hist - Mus musculus [Reaction:R-RNO-390886] HRH4 binds Hist - Rattus norvegicus [Reaction:R-CFA-390886] HRH4 binds Hist - Canis familiaris [Reaction:R-BTA-390886] HRH4 binds Hist - Bos taurus [Reaction:R-DRE-390886] HRH4 binds Hist - Danio rerio [Reaction:R-GGA-390886] HRH4 binds Hist - Gallus gallus [Reaction:R-DME-390886] HRH4 binds Hist - Drosophila melanogaster [Reaction:R-CEL-390886] HRH4 binds Hist - Caenorhabditis elegans [Reaction:R-CEL-390909] HRH2 binds hist - Caenorhabditis elegans [Reaction:R-GGA-390909] HRH2 binds hist - Gallus gallus [Reaction:R-XTR-390909] HRH2 binds hist - Xenopus tropicalis [Reaction:R-DRE-390909] HRH2 binds hist - Danio rerio [Reaction:R-SSC-390909] HRH2 binds hist - Sus scrofa [Reaction:R-BTA-390909] HRH2 binds hist - Bos taurus [Reaction:R-CFA-390909] HRH2 binds hist - Canis familiaris [Reaction:R-RNO-390909] HRH2 binds hist - Rattus norvegicus [Reaction:R-MMU-390909] HRH2 binds hist - Mus musculus [Reaction:R-HSA-390909] HRH2 binds hist - Homo sapiens [Reaction:R-HSA-390912] HRH1 binds hist - Homo sapiens [Reaction:R-MMU-390912] HRH1 binds hist - Mus musculus [Reaction:R-RNO-390912] HRH1 binds hist - Rattus norvegicus [Reaction:R-CFA-390912] HRH1 binds hist - Canis familiaris [Reaction:R-SSC-390912] HRH1 binds hist - Sus scrofa [Reaction:R-XTR-390912] HRH1 binds hist - Xenopus tropicalis [Reaction:R-GGA-390912] HRH1 binds hist - Gallus gallus
created	[InstanceEdit:390914] Jassal, Bijay, 2009-02-11
crossReference	[DatabaseIdentifier:30071] COMPOUND:C00388
dbId	390899
displayName	Hist [extracellular region]
inDisease	false
maxDepth	1
memberOf	[DefinedSet:R-HSA-790205] Ligands of GPCRs that activate Gs [extracellular region] - Homo sapiens [DefinedSet:R-ALL-549264] OCT1 substrates [extracellular region] [DefinedSet:R-HSA-791492] Ligands of GPCRs that activate Gq/11 [extracellular region] - Homo sapiens
modified	[InstanceEdit:9760900] D'Eustachio, Peter, 2022-01-05
name	Hist histamine
positivelyRegulates	[PositiveRegulation:10063301] Positive regulation by 'Hist [extracellular region]' [PositiveRegulation:9941030] Positive regulation by 'Hist [extracellular region]'
referenceEntity	[ReferenceMolecule:chebi:58432] histaminium [ChEBI:58432]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-390899
updateTrackers	[UpdateTracker:9903632] Update Tracker - [SimpleEntity:390899] Hist [extracellular region] - v80:[add_removeReferenceEntity] [UpdateTracker:9874522] Update Tracker - [SimpleEntity:390899] Hist [extracellular region] - v43:[addName] [UpdateTracker:9890661] Update Tracker - [SimpleEntity:390899] Hist [extracellular region] - v52:[modifyName]

Referrals

(hasComponent)	[Complex:R-DME-9692866] HRH3:Hist [plasma membrane] [Complex:R-CEL-9692866] HRH3:Hist [plasma membrane] [Complex:R-GGA-9692866] HRH3:Hist [plasma membrane] [Complex:R-DRE-9692866] HRH3:Hist [plasma membrane] [Complex:R-BTA-9692866] HRH3:Hist [plasma membrane] [Complex:R-CFA-9692866] HRH3:Hist [plasma membrane] [Complex:R-RNO-9692866] HRH3:Hist [plasma membrane] [Complex:R-MMU-9692866] HRH3:Hist [plasma membrane] [Complex:R-SSC-9692866] HRH3:Hist [plasma membrane] [Complex:R-HSA-9692866] HRH3:Hist [plasma membrane] [Complex:R-MMU-390881] HRH2:histamine [plasma membrane] [Complex:R-RNO-390881] HRH2:histamine [plasma membrane] [Complex:R-SSC-390881] HRH2:histamine [plasma membrane] [Complex:R-CEL-390881] HRH2:histamine [plasma membrane] [Complex:R-HSA-390876] HRH4:Hist [plasma membrane] [Complex:R-RNO-390876] HRH4:Hist [plasma membrane] [Complex:R-GGA-390876] HRH4:Hist [plasma membrane] [Complex:R-DME-390876] HRH4:Hist [plasma membrane] [Complex:R-CFA-390876] HRH4:Hist [plasma membrane] [Complex:R-BTA-390876] HRH4:Hist [plasma membrane] [Complex:R-MMU-390876] HRH4:Hist [plasma membrane] [Complex:R-DRE-390876] HRH4:Hist [plasma membrane] [Complex:R-CEL-390876] HRH4:Hist [plasma membrane] [Complex:R-HSA-390885] HRH1:Hist [plasma membrane] [Complex:R-DRE-390885] HRH1:Hist [plasma membrane] [Complex:R-CFA-390885] HRH1:Hist [plasma membrane] [Complex:R-GGA-390885] HRH1:Hist [plasma membrane] [Complex:R-RNO-390885] HRH1:Hist [plasma membrane] [Complex:R-XTR-390885] HRH1:Hist [plasma membrane] [Complex:R-MMU-390885] HRH1:Hist [plasma membrane] [Complex:R-SSC-390885] HRH1:Hist [plasma membrane] [Complex:R-HSA-390881] HRH2:histamine [plasma membrane] [Complex:R-BTA-390881] HRH2:histamine [plasma membrane] [Complex:R-DRE-390881] HRH2:histamine [plasma membrane] [Complex:R-CFA-390881] HRH2:histamine [plasma membrane] [Complex:R-XTR-390881] HRH2:histamine [plasma membrane] [Complex:R-GGA-390881] HRH2:histamine [plasma membrane]
(input)	[Reaction:R-GGA-5696131] AOC1 deaminates Hist [Reaction:R-XTR-5696131] AOC1 deaminates Hist [Reaction:R-DRE-5696131] AOC1 deaminates Hist [Reaction:R-BTA-5696131] AOC1 deaminates Hist [Reaction:R-RNO-5696131] AOC1 deaminates Hist [Reaction:R-MMU-5696131] AOC1 deaminates Hist [Reaction:R-HSA-5696131] AOC1 deaminates Hist [Reaction:R-CEL-9692880] HRH3 binds Hist [Reaction:R-DME-9692880] HRH3 binds Hist [Reaction:R-GGA-9692880] HRH3 binds Hist [Reaction:R-DRE-9692880] HRH3 binds Hist [Reaction:R-SSC-9692880] HRH3 binds Hist [Reaction:R-BTA-9692880] HRH3 binds Hist [Reaction:R-CFA-9692880] HRH3 binds Hist [Reaction:R-RNO-9692880] HRH3 binds Hist [Reaction:R-MMU-9692880] HRH3 binds Hist [Reaction:R-HSA-9692880] HRH3 binds Hist [Reaction:R-CEL-390909] HRH2 binds hist [Reaction:R-GGA-390909] HRH2 binds hist [Reaction:R-XTR-390909] HRH2 binds hist [Reaction:R-DRE-390909] HRH2 binds hist [Reaction:R-SSC-390909] HRH2 binds hist [Reaction:R-BTA-390909] HRH2 binds hist [Reaction:R-CFA-390909] HRH2 binds hist [Reaction:R-RNO-390909] HRH2 binds hist [Reaction:R-MMU-390909] HRH2 binds hist [Reaction:R-HSA-390909] HRH2 binds hist [Reaction:R-HSA-390886] HRH4 binds Hist [Reaction:R-MMU-390886] HRH4 binds Hist [Reaction:R-RNO-390886] HRH4 binds Hist [Reaction:R-CFA-390886] HRH4 binds Hist [Reaction:R-BTA-390886] HRH4 binds Hist [Reaction:R-DRE-390886] HRH4 binds Hist [Reaction:R-GGA-390886] HRH4 binds Hist [Reaction:R-DME-390886] HRH4 binds Hist [Reaction:R-CEL-390886] HRH4 binds Hist [Reaction:R-HSA-390912] HRH1 binds hist [Reaction:R-MMU-390912] HRH1 binds hist [Reaction:R-RNO-390912] HRH1 binds hist [Reaction:R-CFA-390912] HRH1 binds hist [Reaction:R-SSC-390912] HRH1 binds hist [Reaction:R-XTR-390912] HRH1 binds hist [Reaction:R-GGA-390912] HRH1 binds hist
(hasMember)	[DefinedSet:R-ALL-549264] OCT1 substrates [extracellular region] [DefinedSet:R-ALL-549237] OCT2 substrates [extracellular region] [DefinedSet:R-HSA-790205] Ligands of GPCRs that activate Gs [extracellular region] [DefinedSet:R-HSA-791492] Ligands of GPCRs that activate Gq/11 [extracellular region] [DefinedSet:R-BTA-791492] Ligands of GPCRs that activate Gq/11 [extracellular region] [DefinedSet:R-CFA-791492] Ligands of GPCRs that activate Gq/11 [extracellular region] [DefinedSet:R-CEL-791492] Ligands of GPCRs that activate Gq/11 [extracellular region] [DefinedSet:R-MMU-791492] Ligands of GPCRs that activate Gq/11 [extracellular region] [DefinedSet:R-GGA-791492] Ligands of GPCRs that activate Gq/11 [extracellular region]
(regulator)	[PositiveRegulation:10063301] Positive regulation by 'Hist [extracellular region]' [PositiveRegulation:9941030] Positive regulation by 'Hist [extracellular region]'
(updatedInstance)	[UpdateTracker:9903632] Update Tracker - [SimpleEntity:390899] Hist [extracellular region] - v80:[add_removeReferenceEntity] [UpdateTracker:9874522] Update Tracker - [SimpleEntity:390899] Hist [extracellular region] - v43:[addName] [UpdateTracker:9890661] Update Tracker - [SimpleEntity:390899] Hist [extracellular region] - v52:[modifyName]

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