Reactome | HRH4 binds Hist

Schema > Reaction > Entries

category	binding
compartment	[Compartment:984] extracellular region [Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10582926
displayName	HRH4 binds Hist
eventOf	[Pathway:R-DRE-390650] Histamine receptors - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
inferredFrom	[Reaction:R-HSA-390886] HRH4 binds Hist - Homo sapiens
input	[SimpleEntity:R-ALL-390899] Hist [extracellular region] [EntityWithAccessionedSequence:R-DRE-390910] LOC100334962 [plasma membrane]
isInDisease	false
isInferred	true
maxDepth	1
name	HRH4 binds Hist
output	[Complex:R-DRE-390876] HRH4:Hist [plasma membrane]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-390886
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-390650] Histamine receptors
(inferredTo)	[Reaction:R-HSA-390886] HRH4 binds Hist