Reactome | NAd [extracellular region]

Schema > SimpleEntity > Entries

NAd [extracellular region] Show undefined attributes

compartment	[Compartment:984] extracellular region
consumedByEvent	[Reaction:R-HSA-374896] Uptake of Noradrenaline - Homo sapiens [Reaction:R-MMU-374896] Uptake of Noradrenaline - Mus musculus [Reaction:R-RNO-374896] Uptake of Noradrenaline - Rattus norvegicus [Reaction:R-CFA-374896] Uptake of Noradrenaline - Canis familiaris [Reaction:R-BTA-374896] Uptake of Noradrenaline - Bos taurus [Reaction:R-SSC-374896] Uptake of Noradrenaline - Sus scrofa [Reaction:R-DRE-374896] Uptake of Noradrenaline - Danio rerio [Reaction:R-XTR-374896] Uptake of Noradrenaline - Xenopus tropicalis [Reaction:R-GGA-374896] Uptake of Noradrenaline - Gallus gallus [Reaction:R-DME-374896] Uptake of Noradrenaline - Drosophila melanogaster [Reaction:R-CEL-374896] Uptake of Noradrenaline - Caenorhabditis elegans [Reaction:R-HSA-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Homo sapiens [Reaction:R-MMU-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Mus musculus [Reaction:R-RNO-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Rattus norvegicus [Reaction:R-CFA-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Canis familiaris [Reaction:R-BTA-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Bos taurus [Reaction:R-SSC-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Sus scrofa [Reaction:R-DRE-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Danio rerio [Reaction:R-XTR-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Xenopus tropicalis [Reaction:R-GGA-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Gallus gallus [Reaction:R-DME-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Drosophila melanogaster [Reaction:R-CEL-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Caenorhabditis elegans [Reaction:R-PFA-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol - Plasmodium falciparum [Reaction:R-HSA-374919] Noradrenaline clearance from the synaptic cleft - Homo sapiens [Reaction:R-MMU-374919] Noradrenaline clearance from the synaptic cleft - Mus musculus [Reaction:R-RNO-374919] Noradrenaline clearance from the synaptic cleft - Rattus norvegicus [Reaction:R-CFA-374919] Noradrenaline clearance from the synaptic cleft - Canis familiaris [Reaction:R-BTA-374919] Noradrenaline clearance from the synaptic cleft - Bos taurus [Reaction:R-SSC-374919] Noradrenaline clearance from the synaptic cleft - Sus scrofa [Reaction:R-DRE-374919] Noradrenaline clearance from the synaptic cleft - Danio rerio [Reaction:R-XTR-374919] Noradrenaline clearance from the synaptic cleft - Xenopus tropicalis [Reaction:R-GGA-374919] Noradrenaline clearance from the synaptic cleft - Gallus gallus [Reaction:R-DME-374919] Noradrenaline clearance from the synaptic cleft - Drosophila melanogaster [Reaction:R-CEL-374919] Noradrenaline clearance from the synaptic cleft - Caenorhabditis elegans [FailedReaction:R-HSA-5659764] Defective SLC6A2 does not cotransport NAd, Na+ from extracellular region to cytosol - Homo sapiens
created	[InstanceEdit:374906] Mahajan, SS, 2008-08-05 20:29:44
crossReference	[DatabaseIdentifier:30344] COMPOUND:C00547
dbId	374935
displayName	NAd [extracellular region]
inDisease	false
maxDepth	1
memberOf	[DefinedSet:R-ALL-390627] ADR, NAd [extracellular region] [DefinedSet:R-ALL-727774] ligands of SLC29A4 [extracellular region] [DefinedSet:R-ALL-549237] OCT2 substrates [extracellular region]
modified	[InstanceEdit:9817234] D'Eustachio, Peter, 2022-09-14
name	NAd (R)-noradrenaline(1+) Noradrenaline (R)-noradrenaline Norepinephrine
producedByEvent	[Reaction:R-HSA-374899] Release of noradrenaline at the synapse - Homo sapiens [Reaction:R-MMU-374899] Release of noradrenaline at the synapse - Mus musculus [Reaction:R-RNO-374899] Release of noradrenaline at the synapse - Rattus norvegicus [Reaction:R-BTA-374899] Release of noradrenaline at the synapse - Bos taurus [Reaction:R-SSC-374899] Release of noradrenaline at the synapse - Sus scrofa [Reaction:R-DME-374899] Release of noradrenaline at the synapse - Drosophila melanogaster [Reaction:R-CEL-374899] Release of noradrenaline at the synapse - Caenorhabditis elegans
referenceEntity	[ReferenceMolecule:chebi:72587] (R)-noradrenaline(1+) [ChEBI:72587]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-374935
updateTrackers	[UpdateTracker:9891183] Update Tracker - [SimpleEntity:374935] NAd [extracellular region] - v52:[addName] [UpdateTracker:9873740] Update Tracker - [SimpleEntity:374935] NAd [extracellular region] - v43:[addName] [UpdateTracker:9905175] Update Tracker - [SimpleEntity:374935] NAd [extracellular region] - v83:[addName, add_removeReferenceEntity]

Referrals

(input)	[Reaction:R-HSA-374896] Uptake of Noradrenaline [Reaction:R-MMU-374896] Uptake of Noradrenaline [Reaction:R-RNO-374896] Uptake of Noradrenaline [Reaction:R-CFA-374896] Uptake of Noradrenaline [Reaction:R-BTA-374896] Uptake of Noradrenaline [Reaction:R-SSC-374896] Uptake of Noradrenaline [Reaction:R-DRE-374896] Uptake of Noradrenaline [Reaction:R-XTR-374896] Uptake of Noradrenaline [Reaction:R-GGA-374896] Uptake of Noradrenaline [Reaction:R-DME-374896] Uptake of Noradrenaline [Reaction:R-CEL-374896] Uptake of Noradrenaline [Reaction:R-HSA-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-MMU-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-RNO-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-CFA-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-BTA-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-SSC-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-DRE-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-XTR-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-GGA-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-DME-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-CEL-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-PFA-443997] SLC6A2 cotransports NAd, Na+,Cl- from extracellular region to cytosol [Reaction:R-HSA-374919] Noradrenaline clearance from the synaptic cleft [Reaction:R-MMU-374919] Noradrenaline clearance from the synaptic cleft [Reaction:R-RNO-374919] Noradrenaline clearance from the synaptic cleft [Reaction:R-CFA-374919] Noradrenaline clearance from the synaptic cleft [Reaction:R-BTA-374919] Noradrenaline clearance from the synaptic cleft [Reaction:R-SSC-374919] Noradrenaline clearance from the synaptic cleft [Reaction:R-DRE-374919] Noradrenaline clearance from the synaptic cleft [Reaction:R-XTR-374919] Noradrenaline clearance from the synaptic cleft [Reaction:R-GGA-374919] Noradrenaline clearance from the synaptic cleft [Reaction:R-DME-374919] Noradrenaline clearance from the synaptic cleft [Reaction:R-CEL-374919] Noradrenaline clearance from the synaptic cleft [FailedReaction:R-HSA-5659764] Defective SLC6A2 does not cotransport NAd, Na+ from extracellular region to cytosol
(output)	[Reaction:R-HSA-374899] Release of noradrenaline at the synapse [Reaction:R-MMU-374899] Release of noradrenaline at the synapse [Reaction:R-RNO-374899] Release of noradrenaline at the synapse [Reaction:R-BTA-374899] Release of noradrenaline at the synapse [Reaction:R-SSC-374899] Release of noradrenaline at the synapse [Reaction:R-DME-374899] Release of noradrenaline at the synapse [Reaction:R-CEL-374899] Release of noradrenaline at the synapse
(hasMember)	[DefinedSet:R-ALL-390627] ADR, NAd [extracellular region] [DefinedSet:R-ALL-727774] ligands of SLC29A4 [extracellular region] [DefinedSet:R-ALL-549237] OCT2 substrates [extracellular region]
(updatedInstance)	[UpdateTracker:9891183] Update Tracker - [SimpleEntity:374935] NAd [extracellular region] - v52:[addName] [UpdateTracker:9873740] Update Tracker - [SimpleEntity:374935] NAd [extracellular region] - v43:[addName] [UpdateTracker:9905175] Update Tracker - [SimpleEntity:374935] NAd [extracellular region] - v83:[addName, add_removeReferenceEntity]

© 2026 Reactome

Cite Us!