Reactome | Uptake of Noradrenaline

Schema > Reaction > Entries

catalystActivity	[CatalystActivity:10579631] neurotransmitter transmembrane transporter activity of SLC22A1,SLC22A2 [plasma membrane]
category	transition
compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
dbId	10579633
displayName	Uptake of Noradrenaline
eventOf	[Pathway:R-DRE-442660] SLC-mediated transport of neurotransmitters - Danio rerio
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Reaction:R-DRE-374909] Catabolism of Noradrenaline - Danio rerio
inferredFrom	[Reaction:R-HSA-374896] Uptake of Noradrenaline - Homo sapiens
input	[SimpleEntity:R-ALL-374935] NAd [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	Uptake of Noradrenaline
output	[SimpleEntity:R-ALL-209789] NAd [cytosol]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:68323] Danio rerio
stId	R-DRE-374896
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

(hasEvent)	[Pathway:R-DRE-442660] SLC-mediated transport of neurotransmitters [Pathway:R-DRE-181430] Norepinephrine Neurotransmitter Release Cycle
(precedingEvent)	[Reaction:R-DRE-374909] Catabolism of Noradrenaline
(inferredTo)	[Reaction:R-HSA-374896] Uptake of Noradrenaline

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