Reactome | BIL [cytosol]

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BIL [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-9663490] BIL:GSTA1, FABP1 [cytosol] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9709885] BIL scavenges NO - Homo sapiens [BlackBoxEvent:R-HSA-9709879] BIL scavenges O2.- - Homo sapiens [BlackBoxEvent:R-HSA-9709878] BIL translocates to the nucleus - Homo sapiens [Reaction:R-CEL-9663511] BIL binds GSTA1, FABP1 - Caenorhabditis elegans [Reaction:R-DME-9663511] BIL binds GSTA1, FABP1 - Drosophila melanogaster [Reaction:R-GGA-9663511] BIL binds GSTA1, FABP1 - Gallus gallus [Reaction:R-XTR-9663511] BIL binds GSTA1, FABP1 - Xenopus tropicalis [Reaction:R-DRE-9663511] BIL binds GSTA1, FABP1 - Danio rerio [Reaction:R-SSC-9663511] BIL binds GSTA1, FABP1 - Sus scrofa [Reaction:R-BTA-9663511] BIL binds GSTA1, FABP1 - Bos taurus [Reaction:R-CFA-9663511] BIL binds GSTA1, FABP1 - Canis familiaris [Reaction:R-RNO-9663511] BIL binds GSTA1, FABP1 - Rattus norvegicus [Reaction:R-MMU-9663511] BIL binds GSTA1, FABP1 - Mus musculus [BlackBoxEvent:R-HSA-189381] BIL translocates from the cytosol to the ER lumen - Homo sapiens [Reaction:R-HSA-9663511] BIL binds GSTA1, FABP1 - Homo sapiens [Reaction:R-HSA-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Homo sapiens [Reaction:R-MMU-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Mus musculus [Reaction:R-RNO-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Rattus norvegicus [Reaction:R-CFA-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Canis familiaris [Reaction:R-BTA-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Bos taurus [Reaction:R-SSC-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Sus scrofa [Reaction:R-DRE-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Danio rerio [Reaction:R-XTR-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Xenopus tropicalis [Reaction:R-GGA-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Gallus gallus [Reaction:R-DDI-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Dictyostelium discoideum [Reaction:R-SPO-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Schizosaccharomyces pombe [Reaction:R-SCE-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) - Saccharomyces cerevisiae
created	[InstanceEdit:189383] Jassal, Bijay, 2006-11-20
crossReference	[DatabaseIdentifier:30234] COMPOUND:C00486
dbId	189386
displayName	BIL [cytosol]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9760869] D'Eustachio, Peter, 2022-01-04
name	BIL bilirubin bilirubin IXalpha
producedByEvent	[BlackBoxEvent:R-CEL-9663492] BIL dissociates from GSTA1, FABP1 - Caenorhabditis elegans [BlackBoxEvent:R-DME-9663492] BIL dissociates from GSTA1, FABP1 - Drosophila melanogaster [BlackBoxEvent:R-GGA-9663492] BIL dissociates from GSTA1, FABP1 - Gallus gallus [BlackBoxEvent:R-XTR-9663492] BIL dissociates from GSTA1, FABP1 - Xenopus tropicalis [BlackBoxEvent:R-DRE-9663492] BIL dissociates from GSTA1, FABP1 - Danio rerio [BlackBoxEvent:R-SSC-9663492] BIL dissociates from GSTA1, FABP1 - Sus scrofa [BlackBoxEvent:R-BTA-9663492] BIL dissociates from GSTA1, FABP1 - Bos taurus [BlackBoxEvent:R-CFA-9663492] BIL dissociates from GSTA1, FABP1 - Canis familiaris [BlackBoxEvent:R-RNO-9663492] BIL dissociates from GSTA1, FABP1 - Rattus norvegicus [BlackBoxEvent:R-MMU-9663492] BIL dissociates from GSTA1, FABP1 - Mus musculus [Reaction:R-CEL-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Caenorhabditis elegans [Reaction:R-DME-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Drosophila melanogaster [Reaction:R-GGA-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Gallus gallus [Reaction:R-XTR-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Xenopus tropicalis [Reaction:R-DRE-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Danio rerio [Reaction:R-SSC-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Sus scrofa [Reaction:R-BTA-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Bos taurus [Reaction:R-CFA-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Canis familiaris [Reaction:R-RNO-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Rattus norvegicus [Reaction:R-MMU-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Mus musculus [Reaction:R-CEL-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Caenorhabditis elegans [Reaction:R-DME-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Drosophila melanogaster [Reaction:R-GGA-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Gallus gallus [Reaction:R-XTR-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Xenopus tropicalis [Reaction:R-DRE-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Danio rerio [Reaction:R-SSC-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Sus scrofa [Reaction:R-BTA-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Bos taurus [Reaction:R-CFA-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Canis familiaris [Reaction:R-RNO-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Rattus norvegicus [Reaction:R-MMU-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Mus musculus [Reaction:R-HSA-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Homo sapiens [Reaction:R-CEL-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Caenorhabditis elegans [Reaction:R-DME-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Drosophila melanogaster [Reaction:R-GGA-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Gallus gallus [BlackBoxEvent:R-HSA-9663492] BIL dissociates from GSTA1, FABP1 - Homo sapiens [Reaction:R-HSA-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Homo sapiens [Reaction:R-HSA-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL - Homo sapiens [Reaction:R-MMU-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL - Mus musculus [Reaction:R-RNO-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL - Rattus norvegicus [Reaction:R-CFA-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL - Canis familiaris [Reaction:R-BTA-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL - Bos taurus [Reaction:R-SSC-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL - Sus scrofa [Reaction:R-DRE-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL - Danio rerio [Reaction:R-XTR-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL - Xenopus tropicalis [Reaction:R-GGA-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL - Gallus gallus [Reaction:R-DME-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL - Drosophila melanogaster [Reaction:R-HSA-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Homo sapiens [Reaction:R-MMU-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Mus musculus [Reaction:R-RNO-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Rattus norvegicus [Reaction:R-CFA-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Canis familiaris [Reaction:R-BTA-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Bos taurus [Reaction:R-SSC-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Sus scrofa [Reaction:R-DRE-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Danio rerio [Reaction:R-XTR-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) - Xenopus tropicalis
referenceEntity	[ReferenceMolecule:chebi:57977] bilirubin(2-) [ChEBI:57977]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-189386
updateTrackers	[UpdateTracker:9891654] Update Tracker - [SimpleEntity:189386] BIL [cytosol] - v52:[modifyName] [UpdateTracker:9899676] Update Tracker - [SimpleEntity:189386] BIL [cytosol] - v67:[addName] [UpdateTracker:9903256] Update Tracker - [SimpleEntity:189386] BIL [cytosol] - v80:[add_removeReferenceEntity] [UpdateTracker:9874384] Update Tracker - [SimpleEntity:189386] BIL [cytosol] - v43:[addName]

Referrals

(hasComponent)	[Complex:R-HSA-9663490] BIL:GSTA1, FABP1 [cytosol] [Complex:R-GGA-9663490] BIL:GSTA1, FABP1 [cytosol] [Complex:R-CFA-9663490] BIL:GSTA1, FABP1 [cytosol] [Complex:R-SSC-9663490] BIL:GSTA1, FABP1 [cytosol] [Complex:R-DME-9663490] BIL:GSTA1, FABP1 [cytosol] [Complex:R-BTA-9663490] BIL:GSTA1, FABP1 [cytosol] [Complex:R-DRE-9663490] BIL:GSTA1, FABP1 [cytosol] [Complex:R-CEL-9663490] BIL:GSTA1, FABP1 [cytosol] [Complex:R-RNO-9663490] BIL:GSTA1, FABP1 [cytosol] [Complex:R-XTR-9663490] BIL:GSTA1, FABP1 [cytosol] [Complex:R-MMU-9663490] BIL:GSTA1, FABP1 [cytosol]
(input)	[Reaction:R-HSA-9709885] BIL scavenges NO [BlackBoxEvent:R-HSA-9709879] BIL scavenges O2.- [BlackBoxEvent:R-HSA-9709878] BIL translocates to the nucleus [Reaction:R-CEL-9663511] BIL binds GSTA1, FABP1 [Reaction:R-DME-9663511] BIL binds GSTA1, FABP1 [Reaction:R-GGA-9663511] BIL binds GSTA1, FABP1 [Reaction:R-XTR-9663511] BIL binds GSTA1, FABP1 [Reaction:R-DRE-9663511] BIL binds GSTA1, FABP1 [Reaction:R-SSC-9663511] BIL binds GSTA1, FABP1 [Reaction:R-BTA-9663511] BIL binds GSTA1, FABP1 [Reaction:R-CFA-9663511] BIL binds GSTA1, FABP1 [Reaction:R-RNO-9663511] BIL binds GSTA1, FABP1 [Reaction:R-MMU-9663511] BIL binds GSTA1, FABP1 [BlackBoxEvent:R-HSA-189381] BIL translocates from the cytosol to the ER lumen [Reaction:R-HSA-9663511] BIL binds GSTA1, FABP1 [Reaction:R-HSA-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) [Reaction:R-MMU-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) [Reaction:R-RNO-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) [Reaction:R-CFA-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) [Reaction:R-BTA-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) [Reaction:R-SSC-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) [Reaction:R-DRE-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) [Reaction:R-XTR-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) [Reaction:R-GGA-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) [Reaction:R-DDI-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) [Reaction:R-SPO-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood) [Reaction:R-SCE-9661405] ABCC1 transports BIL from cytosol to extracellular region (blood)
(output)	[BlackBoxEvent:R-CEL-9663492] BIL dissociates from GSTA1, FABP1 [BlackBoxEvent:R-DME-9663492] BIL dissociates from GSTA1, FABP1 [BlackBoxEvent:R-GGA-9663492] BIL dissociates from GSTA1, FABP1 [BlackBoxEvent:R-XTR-9663492] BIL dissociates from GSTA1, FABP1 [BlackBoxEvent:R-DRE-9663492] BIL dissociates from GSTA1, FABP1 [BlackBoxEvent:R-SSC-9663492] BIL dissociates from GSTA1, FABP1 [BlackBoxEvent:R-BTA-9663492] BIL dissociates from GSTA1, FABP1 [BlackBoxEvent:R-CFA-9663492] BIL dissociates from GSTA1, FABP1 [BlackBoxEvent:R-RNO-9663492] BIL dissociates from GSTA1, FABP1 [BlackBoxEvent:R-MMU-9663492] BIL dissociates from GSTA1, FABP1 [Reaction:R-CEL-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-DME-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-GGA-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-XTR-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-DRE-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-SSC-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-BTA-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-CFA-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-RNO-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-MMU-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-CEL-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-DME-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-GGA-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-XTR-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-DRE-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-SSC-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-BTA-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-CFA-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-RNO-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-MMU-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-HSA-9661723] SLCO2B1-3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-CEL-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-DME-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-GGA-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [BlackBoxEvent:R-HSA-9663492] BIL dissociates from GSTA1, FABP1 [Reaction:R-HSA-9661799] SLCO1B3 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-HSA-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL [Reaction:R-MMU-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL [Reaction:R-RNO-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL [Reaction:R-CFA-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL [Reaction:R-BTA-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL [Reaction:R-SSC-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL [Reaction:R-DRE-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL [Reaction:R-XTR-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL [Reaction:R-GGA-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL [Reaction:R-DME-189384] BLVRA:Zn2+, BLVRB reduce BV to BIL [Reaction:R-HSA-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-MMU-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-RNO-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-CFA-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-BTA-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-SSC-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-DRE-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte) [Reaction:R-XTR-9661397] SLCO1B1 transports BIL from extracellular region (blood) to cytosol (hepatocyte)
(updatedInstance)	[UpdateTracker:9891654] Update Tracker - [SimpleEntity:189386] BIL [cytosol] - v52:[modifyName] [UpdateTracker:9899676] Update Tracker - [SimpleEntity:189386] BIL [cytosol] - v67:[addName] [UpdateTracker:9903256] Update Tracker - [SimpleEntity:189386] BIL [cytosol] - v80:[add_removeReferenceEntity] [UpdateTracker:9874384] Update Tracker - [SimpleEntity:189386] BIL [cytosol] - v43:[addName]

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