Reactome | PI5P [plasma membrane]

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PI5P [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Homo sapiens [Reaction:R-MMU-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Mus musculus [Reaction:R-RNO-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Rattus norvegicus [Reaction:R-CFA-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Canis familiaris [Reaction:R-BTA-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Bos taurus [Reaction:R-SSC-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Sus scrofa [Reaction:R-DRE-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Danio rerio [Reaction:R-XTR-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Xenopus tropicalis [Reaction:R-GGA-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Gallus gallus [Reaction:R-DME-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Drosophila melanogaster [Reaction:R-CEL-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Caenorhabditis elegans [Reaction:R-DDI-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Dictyostelium discoideum [Reaction:R-SPO-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Schizosaccharomyces pombe [Reaction:R-SCE-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Saccharomyces cerevisiae [Reaction:R-PFA-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane - Plasmodium falciparum
created	[InstanceEdit:1806251] Williams, MG, 2011-10-24
dbId	1806240
displayName	PI5P [plasma membrane]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9760818] D'Eustachio, Peter, 2022-01-03
name	PI5P 1-phosphatidyl-1D-myo-inositol 5-phosphate
negativelyRegulates	[NegativeRegulation:R-HSA-6811496] Negative regulation by 'PI5P [plasma membrane]' [NegativeRegulation:10074140] Negative regulation by 'PI5P [plasma membrane]'
positivelyRegulates	[PositiveRegulation:R-HSA-8858024] Positive regulation by 'PI5P [plasma membrane]' [PositiveRegulation:10077092] Positive regulation by 'PI5P [plasma membrane]'
producedByEvent	[Reaction:R-MMU-6809945] PI(3,5)P2 is dephosphorylated to PI5P by the Mtmr2:Sbf2 tetramer at the plasma membrane - Mus musculus [Reaction:R-HSA-6809944] PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane - Homo sapiens [Reaction:R-CEL-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane - Caenorhabditis elegans [Reaction:R-DME-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane - Drosophila melanogaster [Reaction:R-GGA-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane - Gallus gallus [Reaction:R-DRE-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane - Danio rerio [Reaction:R-SSC-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane - Sus scrofa [Reaction:R-BTA-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane - Bos taurus [Reaction:R-CFA-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane - Canis familiaris [Reaction:R-RNO-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane - Rattus norvegicus [Reaction:R-MMU-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane - Mus musculus [Reaction:R-HSA-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane - Homo sapiens [Reaction:R-HSA-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Homo sapiens [Reaction:R-MMU-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Mus musculus [Reaction:R-MMU-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Mus musculus [Reaction:R-RNO-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Rattus norvegicus [Reaction:R-CFA-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Canis familiaris [Reaction:R-CFA-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Canis familiaris [Reaction:R-HSA-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Homo sapiens [Reaction:R-BTA-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Bos taurus [Reaction:R-BTA-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Bos taurus [Reaction:R-SSC-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Sus scrofa [Reaction:R-SSC-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Sus scrofa [Reaction:R-DRE-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Danio rerio [Reaction:R-DRE-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Danio rerio [Reaction:R-XTR-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Xenopus tropicalis [Reaction:R-XTR-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Xenopus tropicalis [Reaction:R-GGA-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Gallus gallus [Reaction:R-GGA-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Gallus gallus [Reaction:R-DME-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Drosophila melanogaster [Reaction:R-DME-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Drosophila melanogaster [Reaction:R-CEL-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Caenorhabditis elegans [Reaction:R-CEL-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Caenorhabditis elegans [Reaction:R-DDI-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Dictyostelium discoideum [Reaction:R-DDI-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Dictyostelium discoideum [Reaction:R-SPO-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Schizosaccharomyces pombe [Reaction:R-SPO-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Schizosaccharomyces pombe [Reaction:R-SCE-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Saccharomyces cerevisiae [Reaction:R-SCE-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Saccharomyces cerevisiae [Reaction:R-PFA-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane - Plasmodium falciparum [Reaction:R-RNO-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane - Rattus norvegicus
referenceEntity	[ReferenceMolecule:chebi:57795] 1-phosphatidyl-1D-myo-inositol 5-phosphate(3-) [ChEBI:57795]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-1806240
updateTrackers	[UpdateTracker:9903004] Update Tracker - [SimpleEntity:1806240] PI5P [plasma membrane] - v80:[add_removeReferenceEntity]

Referrals

(input)	[Reaction:R-HSA-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-MMU-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-RNO-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-CFA-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-BTA-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-SSC-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-DRE-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-XTR-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-GGA-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-DME-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-CEL-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-DDI-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-SPO-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-SCE-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane [Reaction:R-PFA-1675776] PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane
(output)	[Reaction:R-MMU-6809945] PI(3,5)P2 is dephosphorylated to PI5P by the Mtmr2:Sbf2 tetramer at the plasma membrane [Reaction:R-HSA-6809944] PI(3,5)P2 is dephosphorylated to PI5P by the MTMR2:SBF2 tetramer at the plasma membrane [Reaction:R-CEL-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane [Reaction:R-DME-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane [Reaction:R-GGA-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane [Reaction:R-DRE-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane [Reaction:R-SSC-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane [Reaction:R-BTA-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane [Reaction:R-CFA-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane [Reaction:R-RNO-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane [Reaction:R-MMU-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane [Reaction:R-HSA-6809320] PI(3,5)P2 is dephosphorylated to PI5P by MTMR9-bound MTMR6 or MTMR8 at the plasma membrane [Reaction:R-HSA-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-MMU-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-MMU-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-RNO-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-CFA-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-CFA-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-HSA-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-BTA-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-BTA-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-SSC-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-SSC-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-DRE-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-DRE-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-XTR-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-XTR-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-GGA-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-GGA-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-DME-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-DME-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-CEL-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-CEL-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-DDI-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-DDI-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-SPO-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-SPO-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-SCE-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-SCE-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane [Reaction:R-PFA-1675810] PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane [Reaction:R-RNO-1676203] PI(3,5)P2 is dephosphorylated to PI5P by SYNJ/MTMs at the plasma membrane
(activeUnit)	[NegativeRegulation:R-HSA-6811496] Negative regulation by 'PI5P [plasma membrane]' [PositiveRegulation:R-HSA-8858024] Positive regulation by 'PI5P [plasma membrane]'
(regulator)	[NegativeRegulation:10074140] Negative regulation by 'PI5P [plasma membrane]' [NegativeRegulation:R-HSA-6811496] Negative regulation by 'PI5P [plasma membrane]' [PositiveRegulation:10077092] Positive regulation by 'PI5P [plasma membrane]' [PositiveRegulation:R-HSA-8858024] Positive regulation by 'PI5P [plasma membrane]'
(updatedInstance)	[UpdateTracker:9903004] Update Tracker - [SimpleEntity:1806240] PI5P [plasma membrane] - v80:[add_removeReferenceEntity]

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