Reactome | SAICAR [cytosol]

Schema > SimpleEntity > Entries

SAICAR [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-GGA-419255] 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + fumarate - Gallus gallus [Reaction:R-SCE-73800] SAICAR => AICAR + Fumarate - Saccharomyces cerevisiae [Reaction:R-SPO-73800] SAICAR => AICAR + Fumarate - Schizosaccharomyces pombe [Reaction:R-CEL-73800] SAICAR => AICAR + Fumarate - Caenorhabditis elegans [Reaction:R-DME-73800] SAICAR => AICAR + Fumarate - Drosophila melanogaster [Reaction:R-GGA-73800] SAICAR => AICAR + Fumarate - Gallus gallus [Reaction:R-XTR-73800] SAICAR => AICAR + Fumarate - Xenopus tropicalis [Reaction:R-DRE-73800] SAICAR => AICAR + Fumarate - Danio rerio [Reaction:R-SSC-73800] SAICAR => AICAR + Fumarate - Sus scrofa [Reaction:R-BTA-73800] SAICAR => AICAR + Fumarate - Bos taurus [Reaction:R-CFA-73800] SAICAR => AICAR + Fumarate - Canis familiaris [Reaction:R-RNO-73800] SAICAR => AICAR + Fumarate - Rattus norvegicus [Reaction:R-MMU-73800] SAICAR => AICAR + Fumarate - Mus musculus [Reaction:R-HSA-73800] SAICAR => AICAR + Fumarate - Homo sapiens
created	[InstanceEdit:111398] D'Eustachio, P, 2004-02-13 12:25:00
crossReference	[DatabaseIdentifier:36648] COMPOUND:C04823
dbId	111399
displayName	SAICAR [cytosol]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9734626] D'Eustachio, Peter, 2021-06-17
name	SAICAR SAICAR(4-) 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide
producedByEvent	[Reaction:R-GGA-419223] 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate - Gallus gallus [Reaction:R-CEL-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi - Caenorhabditis elegans [Reaction:R-DME-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi - Drosophila melanogaster [Reaction:R-GGA-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi - Gallus gallus [Reaction:R-XTR-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi - Xenopus tropicalis [Reaction:R-DRE-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi - Danio rerio [Reaction:R-SSC-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi - Sus scrofa [Reaction:R-BTA-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi - Bos taurus [Reaction:R-CFA-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi - Canis familiaris [Reaction:R-RNO-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi - Rattus norvegicus [Reaction:R-MMU-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi - Mus musculus [Reaction:R-HSA-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi - Homo sapiens
referenceEntity	[ReferenceMolecule:chebi:58443] SAICAR(4-) [ChEBI:58443]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-111399
updateTrackers	[UpdateTracker:9902741] Update Tracker - [SimpleEntity:111399] SAICAR [cytosol] - v78:[addName, add_removeReferenceEntity]

Referrals

(updatedInstance)	[UpdateTracker:9902741] Update Tracker - [SimpleEntity:111399] SAICAR [cytosol] - v78:[addName, add_removeReferenceEntity]
(output)	[Reaction:R-GGA-419223] 5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate [Reaction:R-CEL-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi [Reaction:R-DME-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi [Reaction:R-GGA-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi [Reaction:R-XTR-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi [Reaction:R-DRE-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi [Reaction:R-SSC-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi [Reaction:R-BTA-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi [Reaction:R-CFA-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi [Reaction:R-RNO-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi [Reaction:R-MMU-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi [Reaction:R-HSA-73805] CAIR + Aspartate + ATP => SAICAR + ADP + Pi
(input)	[Reaction:R-GGA-419255] 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) <=> 5'-phosphoribosyl-5-aminoimidazole-4-carboxamide (AICAR) + fumarate [Reaction:R-SCE-73800] SAICAR => AICAR + Fumarate [Reaction:R-SPO-73800] SAICAR => AICAR + Fumarate [Reaction:R-CEL-73800] SAICAR => AICAR + Fumarate [Reaction:R-DME-73800] SAICAR => AICAR + Fumarate [Reaction:R-GGA-73800] SAICAR => AICAR + Fumarate [Reaction:R-XTR-73800] SAICAR => AICAR + Fumarate [Reaction:R-DRE-73800] SAICAR => AICAR + Fumarate [Reaction:R-SSC-73800] SAICAR => AICAR + Fumarate [Reaction:R-BTA-73800] SAICAR => AICAR + Fumarate [Reaction:R-CFA-73800] SAICAR => AICAR + Fumarate [Reaction:R-RNO-73800] SAICAR => AICAR + Fumarate [Reaction:R-MMU-73800] SAICAR => AICAR + Fumarate [Reaction:R-HSA-73800] SAICAR => AICAR + Fumarate

© 2026 Reactome

Cite Us!