Reactome | Positive gene expression regulation by 'Sirt1 [nucleoplasm]'

Schema > PositiveGeneExpressionRegulation > Entries

created	[InstanceEdit:9931532] May, Bruce, 2024-12-12
dbId	9931507
displayName	Positive gene expression regulation by 'Sirt1 [nucleoplasm]'
regulatedEntity	[BlackBoxEvent:R-MMU-9932080] Rora,c and coactivators positively regulate expression of Clock - Mus musculus [BlackBoxEvent:R-MMU-9911570] Rora,b,c positivley regulates and Nr1d1 (Rev-erba) negatively regulates expression of Bmal1 (Arntl) - Mus musculus
regulator	[EntityWithAccessionedSequence:R-MMU-5211238] Sirt1 [nucleoplasm]
schemaClass	PositiveGeneExpressionRegulation

(regulatedBy)	[BlackBoxEvent:R-MMU-9932080] Rora,c and coactivators positively regulate expression of Clock [BlackBoxEvent:R-MMU-9911570] Rora,b,c positivley regulates and Nr1d1 (Rev-erba) negatively regulates expression of Bmal1 (Arntl)
(regulation)	[RegulationReference:9931526] Positive gene expression regulation by 'Sirt1 [nucleoplasm]' SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging

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