Reactome | Positive regulation by 'P2RY2:ATP [plasma membrane]'

Schema > PositiveRegulation > Entries

created	[InstanceEdit:9861467] May, Bruce, 2024-02-21
dbId	9861496
displayName	Positive regulation by 'P2RY2:ATP [plasma membrane]'
regulatedEntity	[BlackBoxEvent:R-HSA-9860796] Phosphorylation of PDPK1 on serine-241 - Homo sapiens [Reaction:R-HSA-9855161] Pannexin-1 (PANX1) channel transports ATP from the cytosol to the extracellular region - Homo sapiens
regulator	[Complex:R-HSA-9860834] P2RY2:ATP [plasma membrane]
schemaClass	PositiveRegulation

(regulatedBy)	[BlackBoxEvent:R-HSA-9860796] Phosphorylation of PDPK1 on serine-241 [Reaction:R-HSA-9855161] Pannexin-1 (PANX1) channel transports ATP from the cytosol to the extracellular region
(regulation)	[RegulationReference:9905996] Positive regulation by 'P2RY2:ATP [plasma membrane]' Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium

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