Reactome | P2RY2:ATP [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:9860774] May, Bruce, 2024-02-10
dbId	9860834
displayName	P2RY2:ATP [plasma membrane]
hasComponent	[SimpleEntity:R-ALL-114570] ATP [extracellular region] [EntityWithAccessionedSequence:R-HSA-417923] P2RY2 [plasma membrane]
inDisease	false
includedLocation	[Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-9860834] P2RY2:ATP [plasma membrane] - Mus musculus [Complex:R-RNO-9860834] P2RY2:ATP [plasma membrane] - Rattus norvegicus [Complex:R-CFA-9860834] P2RY2:ATP [plasma membrane] - Canis familiaris [Complex:R-BTA-9860834] P2RY2:ATP [plasma membrane] - Bos taurus [Complex:R-SSC-9860834] P2RY2:ATP [plasma membrane] - Sus scrofa [Complex:R-DRE-9860834] P2RY2:ATP [plasma membrane] - Danio rerio [Complex:R-XTR-9860834] P2RY2:ATP [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-9860834] P2RY2:ATP [plasma membrane] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:9860803] Protein kinase N2 mediates flow-induced endothelial NOS activation and vascular tone regulation
maxDepth	2
name	P2RY2:ATP
positivelyRegulates	[PositiveRegulation:9861496] Positive regulation by 'P2RY2:ATP [plasma membrane]'
producedByEvent	[Reaction:R-HSA-9860787] P2RY2 binds ATP - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-9860834

(requiredInputComponent)	[Reaction:R-HSA-9860785] PDPK1 (PDK1) phosphorylates PKN2 on threonine-816
(output)	[Reaction:R-HSA-9860787] P2RY2 binds ATP
(regulator)	[PositiveRegulation:9861496] Positive regulation by 'P2RY2:ATP [plasma membrane]'