Reactome | Negative regulation by 'BRCA1 [nucleoplasm]'

Schema > NegativeRegulation > Entries

activity	[GO_MolecularFunction:9758016] molecular function inhibitor activity
created	[InstanceEdit:9817832] Tiwari, Krishna, 2022-09-27
dbId	9817830
displayName	Negative regulation by 'BRCA1 [nucleoplasm]'
modified	[InstanceEdit:9817933] Tiwari, Krishna, 2022-09-30
regulatedEntity	[Reaction:R-HSA-8932327] NFE2L2 binds KEAP1:NEDD8-CUL3:RBX1 - Homo sapiens
regulator	[EntityWithAccessionedSequence:R-HSA-50949] BRCA1 [nucleoplasm]
schemaClass	NegativeRegulation

(regulation)	[RegulationReference:9817834] Negative regulation by 'BRCA1 [nucleoplasm]' BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival
(regulatedBy)	[Reaction:R-HSA-8932327] NFE2L2 binds KEAP1:NEDD8-CUL3:RBX1

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