Reactome | Negative regulation by 'factor Xa:Factor Xa inhibitors [plasma membrane]' Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor

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created	[InstanceEdit:9735231] Jassal, Bijay, 2021-06-23
dbId	9735230
displayName	Negative regulation by 'factor Xa:Factor Xa inhibitors [plasma membrane]' Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor
literatureReference	[LiteratureReference:9038770] Discovery of betrixaban (PRT054021), N-(5-chloropyridin-2-yl)-2-(4-(N,N-dimethylcarbamimidoyl)benzamido)-5-methoxybenzamide, a highly potent, selective, and orally efficacious factor Xa inhibitor [LiteratureReference:9015065] Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor [LiteratureReference:9038773] Edoxaban, a Novel Oral Factor Xa Inhibitor [LiteratureReference:9603677] Efficacy and toxicity of factor Xa inhibitors [LiteratureReference:9038767] The new factor Xa inhibitor: Apixaban
regulatedBy	[NegativeRegulation:R-HSA-9015052] Negative regulation by 'factor Xa:Factor Xa inhibitors [plasma membrane]'
schemaClass	RegulationReference

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