Reactome | Positive regulation by 'GSDMD pore complex [plasma membrane]'

Schema > PositiveRegulation > Entries

created	[InstanceEdit:9710338] Shamovsky, Veronica, 2020-12-28
dbId	9710340
displayName	Positive regulation by 'GSDMD pore complex [plasma membrane]'
modified	[InstanceEdit:9716274] Shamovsky, Veronica, 2021-02-19
regulatedEntity	[BlackBoxEvent:R-HSA-449058] Interleukin-1 family are secreted - Homo sapiens [BlackBoxEvent:R-HSA-6805981] HMGB1 release from cells - Homo sapiens
regulator	[Complex:R-HSA-9647630] GSDMD pore complex [plasma membrane]
schemaClass	PositiveRegulation

(regulation)	[RegulationReference:9710339] Positive regulation by 'GSDMD pore complex [plasma membrane]' Progressive waves of IL-1? release by primary human monocytes via sequential activation of vesicular and gasdermin D-mediated secretory pathways [RegulationReference:9710383] Positive regulation by 'GSDMD pore complex [plasma membrane]' Indirect regulation of HMGB1 release by gasdermin D
(regulatedBy)	[BlackBoxEvent:R-HSA-449058] Interleukin-1 family are secreted [BlackBoxEvent:R-HSA-6805981] HMGB1 release from cells

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