Reactome | Negative regulation by 'p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:FLOT1:FLOT2 [plasma membrane]'

Schema > NegativeRegulation > Entries

activeUnit	[Complex:R-HSA-9688487] FLOT1:FLOT2 [plasma membrane] - Homo sapiens
created	[InstanceEdit:9692658] Shamovsky, Veronica, 2020-06-25
dbId	9692657
displayName	Negative regulation by 'p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:FLOT1:FLOT2 [plasma membrane]'
regulatedEntity	[Reaction:R-HSA-5620975] MLKL binds PIPs - Homo sapiens
regulator	[Complex:R-HSA-9688468] p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:FLOT1:FLOT2 [plasma membrane]
schemaClass	NegativeRegulation

(regulation)	[RegulationReference:9692660] Negative regulation by 'p-S-RIPK1:p-S199,227-RIPK3:p-T357,S358-MLKL oligomer:FLOT1:FLOT2 [plasma membrane]' Flotillin-mediated endocytosis and ALIX-syntenin-1-mediated exocytosis protect the cell membrane from damage caused by necroptosis
(regulatedBy)	[Reaction:R-HSA-5620975] MLKL binds PIPs

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