Reactome | Requirement by 'RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]'

Schema > Requirement > Entries

activeUnit	[EntityWithAccessionedSequence:R-HSA-6810227] RPAP2 [nucleoplasm] - Homo sapiens
activity	[GO_MolecularFunction:14173] protein serine/threonine phosphatase activity
created	[InstanceEdit:9685237] May, Bruce, 2020-04-23
dbId	9685235
displayName	Requirement by 'RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]'
modified	[InstanceEdit:9983308] Weiser, Joel, 2026-02-22
regulatedEntity	[BlackBoxEvent:R-HSA-6814559] Pre-snRNA is elongated and capped with 7-methylguanosine - Homo sapiens
regulator	[Complex:R-HSA-6814534] RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]
schemaClass	Requirement

(regulation)	[RegulationReference:9685238] Requirement by 'RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm]' Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes
(regulatedBy)	[BlackBoxEvent:R-HSA-6814559] Pre-snRNA is elongated and capped with 7-methylguanosine

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